Enzymatic Complex Summary
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SURF complex from Homo sapiens
Known also as: |
SMG1-UPF1-eRF1-eRF3 complex |
Structure of SURF complex (Homo sapiens):
In EJC-dependent NMD, the SURF complex associates with the exon junction complex (EJC) through UPF2 and allows the formation of an UPF1-UPF2-UPF3 surveillance complex which is believed to activate NMD
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Reactions in which SURF complex is involved:
Pathways in which SURF complex is involved:
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Last modification of this entry: May 16, 2012.
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