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Bujnicki Lab Homepage

tRNA nuclear surveillance in Saccharomyces cerevisiae

Enzymatic
complexes:
Exosome
TRAMP complex


Nuclear pre-tRNAiMet lacking m1A58 is subject to polyadenylation by Trf4 of the TRAMP complex, and then degradation by Rrp6 and the nuclear exosome. [PMID: 15145828, 16431988,  for review, see: 20810645]




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Last modification of this entry: Sept. 24, 2012.

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