Known also as: 40 kDa CCR4-associated factor
Known abbreviations: CAF40
Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.
Subunit of the 1.0 MDa CCR4-NOT core complex that contains CCR4, CAF1, NOT1, NOT2, NOT3, NOT4, NOT5, CAF40 and CAF130. In the complex interacts with NOT1. The core complex probably is part of a less characterized 1.9 MDa CCR4-NOT complex.
Cytoplasm (Probable). Nucleus (Probable).
This protein can be a part of a given complexes:
Activities in which Protein CAF40 is involved:
Pathways in which Protein CAF40 is involved:
Links to other databases:
Protein CAF40 (Saccharomyces cerevisiae) is product of expression of
||Publication date (Issue)
|The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
||Philippsen P, Kleine K, Pohlmann R, Dusterhoft A, Hamberg K, Hegemann JH, Obermaier B, Urrestarazu LA, Aert R, Albermann K
|Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex.
||Chen J, Rappsilber J, Chiang YC, Russell P, Mann M, Denis CL
J Mol Biol
|Global analysis of protein expression in yeast.
||Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS
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Entry added on: 2010-04-12 22:49:22, by a user: kaja