Known also as: Eukaryotic release factor 1
Known abbreviations: eRF1, ETF1, ERF1, RF1, SUP45L1, Protein Cl1, TB3-1
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Heterodimer of two subunits, one of which binds GTP. Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex.
This protein can be a part of a given complexes:
Activities in which Eukaryotic peptide chain release factor subunit 1 is involved:
Pathways in which Eukaryotic peptide chain release factor subunit 1 is involved:
Links to other databases:
Eukaryotic peptide chain release factor subunit 1 (Homo sapiens) is product of expression of
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Last modification of this entry: Sept. 25, 2012.