Known also as: Nucleolar protein 10,Nucleolar protein family A member 3,snoRNP protein NOP10
Known abbreviations: NOP10,YHR072W-A
Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.
Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs). The protein component of the H/ACA snoRNP contains CBF5, GAR1, NHP2 and NOP10. The complex contains a stable core composed of CBF5 and NOP10, to which GAR1 and NHP2 subsequently bind.
Nucleus › nucleolus
This protein can be a part of a given complexes:
Activities in which H/ACA ribonucleoprotein complex subunit 3 is involved:
Pathways in which H/ACA ribonucleoprotein complex subunit 3 is involved:
Links to other databases:
H/ACA ribonucleoprotein complex subunit 3 (Saccharomyces cerevisiae) is product of expression of
||Publication date (Issue)
|Global analysis of protein localization in budding yeast.
||Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK
|Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
||Johnston M, Andrews S, Brinkman R, Cooper J, Ding H, Dover J, Du Z, Favello A, Fulton L, Gattung S, et al.
|Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
||Hu Y, Rolfs A, Bhullar B, Murthy TV, Zhu C, Berger MF, Camargo AA, Kelley F, McCarron S, Jepson D, Richardson A, Raphael J, Moreira D, Taycher E, Zuo D, Mohr S, Kane MF, Williamson J, Simpson A, Bulyk ML, Harlow E, Marsischky G, Kolodner RD, LaBaer J
|Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
||Chi A, Huttenhower C, Geer LY, Coon JJ, Syka JE, Bai DL, Shabanowitz J, Burke DJ, Troyanskaya OG, Hunt DF
Proc Natl Acad Sci U S A
|Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.
||Henras A, Henry Y, Bousquet-Antonelli C, Noaillac-Depeyre J, Gelugne JP, Caizergues-Ferrer M...
|Cbf5p, the putative pseudouridine synthase of H/ACA-type snoRNPs, can form a complex with Gar1p and Nop10p in absence of Nhp2p and box H/ACA snoRNAs.
||Henras AK, Capeyrou R, Henry Y, Caizergues-Ferrer M...
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Last modification of this entry: April 26, 2013.