Known abbreviations: NAF1
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.
During assembly of the complex, component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs) which contains NOLA2/NHP2, NOLA3/NOP10, NAF1 and DKC1/NOLA4. Interacts directly with DKC1/NOLA4.
Cytoplasm. Nucleus. Note: Shuttles between the cytoplasm and the nucleus. Absent from the nucleolus
Belongs to the NAF1 family.
Activities in which H/ACA ribonucleoprotein complex non-core subunit NAF1 is involved:
Pathways in which H/ACA ribonucleoprotein complex non-core subunit NAF1 is involved:
Links to other databases:
H/ACA ribonucleoprotein complex non-core subunit NAF1 (Homo sapiens) is product of expression of
nuclear assembly factor 1 ribonucleoprotein
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Last modification of this entry: July 17, 2013.