Modomics - A Database of RNA Modifications

ID Card:

Full name: tRNA (guanine-N(7)-)-methyltransferase
UniProt: Q5SHW1
Alpha Fold Predicted Structure: AF-Q5SHW1-F1
Enzyme type: methyltransferase



Protein sequence:

MLVVPARLHRWPPEVQDLFGREGPLVLEIGFGDGRFTAELARSRPDWLVLGAEVSAASVLRALRRMRREGLANVRLYHGQGPFALRNLVLPGTLDQVIVNFPDPWPKKRHQERRLLREAFFRRLSTRLKPGGSLLLTTDHEEYFRFALEEAERTGLYRVEVRPPPEAHLRTKYALKWKEAGRAFFHAAFIKLREDPAPWPPLRRYDVAHALLSGELPQDLALEKTPVRLKEGVAVFLEVARGKEGFYVLTHVEEEDLTQDLLLEVRKSARGVYAGVSRFGSPLITEAVKGAVRALVDRLEAHGLEVVQDHT

Comments:

Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.





Alpha Fold Predicted Structure:






Clear Selection and Reset Camera

Protein sequence:

M L V V P A R L H R W P P E V Q D L F G R E G P L V L E I G F G D G R F T A E L A R S R P D W L V L G A E V S A A S V L R A L R R M R R E G L A N V R L Y H G Q G P F A L R N L V L P G T L D Q V I V N F P D P W P K K R H Q E R R L L R E A F F R R L S T R L K P G G S L L L T T D H E E Y F R F A L E E A E R T G L Y R V E V R P P P E A H L R T K Y A L K W K E A G R A F F H A A F I K L R E D P A P W P P L R R Y D V A H A L L S G E L P Q D L A L E K T P V R L K E G V A V F L E V A R G K E G F Y V L T H V E E E D L T Q D L L L E V R K S A R G V Y A G V S R F G S P L I T E A V K G A V R A L V D R L E A H G L E V V Q D H T

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-Q5SHW1-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-Q5SHW1-F1.cif  
DSSP Secondary Structures   Q5SHW1.dssp  





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