ID Card:
Full name:
NOL1/NOP2/sun family protein / antitermination NusB domain-containing protein
UniProt:
Q8VYC4
Alpha Fold Predicted Structure:
AF-Q8VYC4-F1
Enzyme type:
methyltransferase
Protein sequence:
MAQLLSFRVYLSAETQKASPGSFKRTQKTRKPFSPDRRGPVAPSRKSQNLNLEVSPHRAVSAVRLMRIEYGGAFADLLNEKGKGSGSNEMSYVERTIGFRTRDLDDRDLRLVTDVVGGTIRWRRYLDHLIGSLCHNERTFRNMEPLLLQILRIGVYEIIKRDMPPYAVVDENVRLAKVALRPGAGDFVNGILRKLVSLKEKDALPLPKVEGDDRAQARALATLHSHPVWMVRRWVKYLGLDEATKLMIWNNNDPGFSLRANTGRDITRADLVERLNSLKVPHELSLHLEEFVRIKTGLQTVVQAGLLKEGICSVQDESAGLIVSVVKPQPGERIMDACAAPGGKTLFMASCLKGQGMIYAMDVNEGRLRILGETAKSHQVDGLITTIHSDLRVFAETNEVQYDKVLLDAPCSGLGVLSKRADLRWNRKLEDMLELTKLQDELLDSASKLVKHGGVLVYSTCSIDPEENEGRVEAFLLRHPEFTIDPVTSFVPSSFVTSQGFFLSNPVKHSLDGAFAARLVRAL
Comments:
tRNA m5C methyltransferase contributing to an early and sensitive bolting/flowering phenotype, suggesting that the timing of bolting and flowering is also regulated at the epitranscriptomic level.
Alpha Fold Predicted Structure:
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Protein sequence:
M
A
Q
L
L
S
F
R
V
Y
L
S
A
E
T
Q
K
A
S
P
G
S
F
K
R
T
Q
K
T
R
K
P
F
S
P
D
R
R
G
P
V
A
P
S
R
K
S
Q
N
L
N
L
E
V
S
P
H
R
A
V
S
A
V
R
L
M
R
I
E
Y
G
G
A
F
A
D
L
L
N
E
K
G
K
G
S
G
S
N
E
M
S
Y
V
E
R
T
I
G
F
R
T
R
D
L
D
D
R
D
L
R
L
V
T
D
V
V
G
G
T
I
R
W
R
R
Y
L
D
H
L
I
G
S
L
C
H
N
E
R
T
F
R
N
M
E
P
L
L
L
Q
I
L
R
I
G
V
Y
E
I
I
K
R
D
M
P
P
Y
A
V
V
D
E
N
V
R
L
A
K
V
A
L
R
P
G
A
G
D
F
V
N
G
I
L
R
K
L
V
S
L
K
E
K
D
A
L
P
L
P
K
V
E
G
D
D
R
A
Q
A
R
A
L
A
T
L
H
S
H
P
V
W
M
V
R
R
W
V
K
Y
L
G
L
D
E
A
T
K
L
M
I
W
N
N
N
D
P
G
F
S
L
R
A
N
T
G
R
D
I
T
R
A
D
L
V
E
R
L
N
S
L
K
V
P
H
E
L
S
L
H
L
E
E
F
V
R
I
K
T
G
L
Q
T
V
V
Q
A
G
L
L
K
E
G
I
C
S
V
Q
D
E
S
A
G
L
I
V
S
V
V
K
P
Q
P
G
E
R
I
M
D
A
C
A
A
P
G
G
K
T
L
F
M
A
S
C
L
K
G
Q
G
M
I
Y
A
M
D
V
N
E
G
R
L
R
I
L
G
E
T
A
K
S
H
Q
V
D
G
L
I
T
T
I
H
S
D
L
R
V
F
A
E
T
N
E
V
Q
Y
D
K
V
L
L
D
A
P
C
S
G
L
G
V
L
S
K
R
A
D
L
R
W
N
R
K
L
E
D
M
L
E
L
T
K
L
Q
D
E
L
L
D
S
A
S
K
L
V
K
H
G
G
V
L
V
Y
S
T
C
S
I
D
P
E
E
N
E
G
R
V
E
A
F
L
L
R
H
P
E
F
T
I
D
P
V
T
S
F
V
P
S
S
F
V
T
S
Q
G
F
F
L
S
N
P
V
K
H
S
L
D
G
A
F
A
A
R
L
V
R
A
L
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
Publications:
Title
Authors
Journal
Details
PubMed Id DOI
RNA methyltransferases in plants: Breakthroughs in function and evolution
Ricardo Ferraz 1, Sílvia Coimbra 2, Sandra Correia 3, Jorge Canhoto 4
[details]
36502609
10.1016/j.plaphy.2022.12.001