General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000540846
Gene ID:	ENSG00000166949
Gene Name:	SMAD3
Sequence (UNICHARACTER ENCODING)	AAAUAUGAGCUUGUGCUUGCUGGAGGAGGAUGACAGAGGAGCCUGCUGCUGAGUUCACUGGUGCUGGGGUUAGGUCACUGCUGGGCUGAAGCGCACUGACCAUAAGAGCAACAUGUGGGCAAGAGCCGCGGCACUGGGGUAAUUUAUUGCCGCCGCUCGCUUCACCAGGAACCCCACACGCUGGGUUCCCACAGGAUGCGACAUUCCCACAGGAUGGGACAACUGCAUGGAAACCCACACUCGGGCCUGUGUUGAGCAACCACGUUUGAGUCCCUGGAUGGCCGGUUGCAGGUGUCCCAUCGGAAGGGGCUCCCUCAUGUCAUCUACUGCCGCCUGUGGCGAUGGCCAGACCUGCACAGCCACCACGAGCUACGGGCCAUGGAGCUGUGUGAGUUCGCCUUCAAUAUGAAGAAGGACGAGGUCUGCGUGAAUCCCUACCACUACCAGAGAGUAGAGACACCAGUUCUACCUCCUGUGUUGGUGCCACGCCACACAGAGAUCCCGGCCGAGUUCCCCCCACUGGACGACUACAGCCAUUCCAUCCCCGAAAACACUAЖCUUCCCCGCAGGCAUCGAGCCCCAGAGCAAUAUUCCAGAGACCCCACCCCCUGGCUACCUGAGUGAAGAUGGAGAAACCAGUGACCACCAGAUGAЖCCACAGCAUGGACGCAGGUUCUCCAAACCUAUCCCCGAAUCCGAUGUCCCCAGCACAUAAUAACUUGGЖCCUGCAGCCAGUUACCUACUGCGAGCCGGCCUUCUGGUGCUCCAUCUCCUACUACGAGCUGAACCAGCGCGUCGGGGAGACAUUCCACGCCUCGCAGCCAPCCAUGACUGUGGAUGGCUUCACCGACCCCUCCAAUUCGGAGCGCUUCUGCCUAGGGCUGCUCUCCAAUGUCAACAGGAAUGCAGCAGUGGAGCUGACACGGAGACACAUCGGAAGAGGCGUGCGGCUCUACUACAUCGGAGGGGAGGUCUUCGCAGAGUGCCUCAGUGACAGCGCUAUUUUUGUCCAGUCUCCCAACUGUAACCAGCGCUAUGGCUGGCACCCGGCCACCGUCUGCAAGAUCCCACCAGGAUGCAACCUGAAGAUCUUCAACAACCAGGAGUUCGCUGCCCUCCUGGCCCAGUCGGUCAACCAGGGCUUUGAGGCUGUCUACCAGUUGACCCGAAUGUGCACCAUCCGCAUGAGCUUCGUCAAAGGCUGGGGAGCGGAGUACAGGAGACAGACUGUGЖCCAGUACCCCCUGCUGGAUUGAGCUGCACCUGAAUGGGCCUUUGCAGUGGCUUGACAAGGUCCUCACCCAGAUGGGCUCCCCAAGCAUCCGCUGUUCCAGUGUGUCUUAGAGЖCAUCAAGUAUGGUAGGGGAGGGCAGGCUUGGGGAAAAUGGCCAUGCAGGAGGUGGAGAAAAUUGGAЖCUCUACUCAACCCAUUGUUGUCAAGGAAGAAGAAAUCUUUCUCCCUCAACUGAAGGGGUGCACCCACCUGUUUUCUGAAACACACGAGCAAACCCAGAGGUGGAUGUUAUGAЖCAGCUGUGUCUGCCAAACACAUUUACCCUUUGGCCCCACUUUG
Sequence (SHORT NAMES ENCODING)	AAAUAUGAGCUUGUGCUUGCUGGAGGAGGAUGACAGAGGAGCCUGCUGCUGAGUUCACUGGUGCUGGGGUUAGGUCACUGCUGGGCUGAAGCGCACUGACCAUAAGAGCAACAUGUGGGCAAGAGCCGCGGCACUGGGGUAAUUUAUUGCCGCCGCUCGCUUCACCAGGAACCCCACACGCUGGGUUCCCACAGGAUGCGACAUUCCCACAGGAUGGGACAACUGCAUGGAAACCCACACUCGGGCCUGUGUUGAGCAACCACGUUUGAGUCCCUGGAUGGCCGGUUGCAGGUGUCCCAUCGGAAGGGGCUCCCUCAUGUCAUCUACUGCCGCCUGUGGCGAUGGCCAGACCUGCACAGCCACCACGAGCUACGGGCCAUGGAGCUGUGUGAGUUCGCCUUCAAUAUGAAGAAGGACGAGGUCUGCGUGAAUCCCUACCACUACCAGAGAGUAGAGACACCAGUUCUACCUCCUGUGUUGGUGCCACGCCACACAGAGAUCCCGGCCGAGUUCCCCCCACUGGACGACUACAGCCAUUCCAUCCCCGAAAACACUAm6ACUUCCCCGCAGGCAUCGAGCCCCAGAGCAAUAUUCCAGAGACCCCACCCCCUGGCUACCUGAGUGAAGAUGGAGAAACCAGUGACCACCAGAUGAm6ACCACAGCAUGGACGCAGGUUCUCCAAACCUAUCCCCGAAUCCGAUGUCCCCAGCACAUAAUAACUUGGm6ACCUGCAGCCAGUUACCUACUGCGAGCCGGCCUUCUGGUGCUCCAUCUCCUACUACGAGCUGAACCAGCGCGUCGGGGAGACAUUCCACGCCUCGCAGCCAYCCAUGACUGUGGAUGGCUUCACCGACCCCUCCAAUUCGGAGCGCUUCUGCCUAGGGCUGCUCUCCAAUGUCAACAGGAAUGCAGCAGUGGAGCUGACACGGAGACACAUCGGAAGAGGCGUGCGGCUCUACUACAUCGGAGGGGAGGUCUUCGCAGAGUGCCUCAGUGACAGCGCUAUUUUUGUCCAGUCUCCCAACUGUAACCAGCGCUAUGGCUGGCACCCGGCCACCGUCUGCAAGAUCCCACCAGGAUGCAACCUGAAGAUCUUCAACAACCAGGAGUUCGCUGCCCUCCUGGCCCAGUCGGUCAACCAGGGCUUUGAGGCUGUCUACCAGUUGACCCGAAUGUGCACCAUCCGCAUGAGCUUCGUCAAAGGCUGGGGAGCGGAGUACAGGAGACAGACUGUGm6ACCAGUACCCCCUGCUGGAUUGAGCUGCACCUGAAUGGGCCUUUGCAGUGGCUUGACAAGGUCCUCACCCAGAUGGGCUCCCCAAGCAUCCGCUGUUCCAGUGUGUCUUAGAGm6ACAUCAAGUAUGGUAGGGGAGGGCAGGCUUGGGGAAAAUGGCCAUGCAGGAGGUGGAGAAAAUUGGAm6ACUCUACUCAACCCAUUGUUGUCAAGGAAGAAGAAAUCUUUCUCCCUCAACUGAAGGGGUGCACCCACCUGUUUUCUGAAACACACGAGCAAACCCAGAGGUGGAUGUUAUGAm6ACAGCUGUGUCUGCCAAACACAUUUACCCUUUGGCCCCACUUUG
Sequence (MODOMICS CODE ENCODING)	AAAUAUGAGCUUGUGCUUGCUGGAGGAGGAUGACAGAGGAGCCUGCUGCUGAGUUCACUGGUGCUGGGGUUAGGUCACUGCUGGGCUGAAGCGCACUGACCAUAAGAGCAACAUGUGGGCAAGAGCCGCGGCACUGGGGUAAUUUAUUGCCGCCGCUCGCUUCACCAGGAACCCCACACGCUGGGUUCCCACAGGAUGCGACAUUCCCACAGGAUGGGACAACUGCAUGGAAACCCACACUCGGGCCUGUGUUGAGCAACCACGUUUGAGUCCCUGGAUGGCCGGUUGCAGGUGUCCCAUCGGAAGGGGCUCCCUCAUGUCAUCUACUGCCGCCUGUGGCGAUGGCCAGACCUGCACAGCCACCACGAGCUACGGGCCAUGGAGCUGUGUGAGUUCGCCUUCAAUAUGAAGAAGGACGAGGUCUGCGUGAAUCCCUACCACUACCAGAGAGUAGAGACACCAGUUCUACCUCCUGUGUUGGUGCCACGCCACACAGAGAUCCCGGCCGAGUUCCCCCCACUGGACGACUACAGCCAUUCCAUCCCCGAAAACACUA2000000006ACUUCCCCGCAGGCAUCGAGCCCCAGAGCAAUAUUCCAGAGACCCCACCCCCUGGCUACCUGAGUGAAGAUGGAGAAACCAGUGACCACCAGAUGA2000000006ACCACAGCAUGGACGCAGGUUCUCCAAACCUAUCCCCGAAUCCGAUGUCCCCAGCACAUAAUAACUUGG2000000006ACCUGCAGCCAGUUACCUACUGCGAGCCGGCCUUCUGGUGCUCCAUCUCCUACUACGAGCUGAACCAGCGCGUCGGGGAGACAUUCCACGCCUCGCAGCCA2000000009UCCAUGACUGUGGAUGGCUUCACCGACCCCUCCAAUUCGGAGCGCUUCUGCCUAGGGCUGCUCUCCAAUGUCAACAGGAAUGCAGCAGUGGAGCUGACACGGAGACACAUCGGAAGAGGCGUGCGGCUCUACUACAUCGGAGGGGAGGUCUUCGCAGAGUGCCUCAGUGACAGCGCUAUUUUUGUCCAGUCUCCCAACUGUAACCAGCGCUAUGGCUGGCACCCGGCCACCGUCUGCAAGAUCCCACCAGGAUGCAACCUGAAGAUCUUCAACAACCAGGAGUUCGCUGCCCUCCUGGCCCAGUCGGUCAACCAGGGCUUUGAGGCUGUCUACCAGUUGACCCGAAUGUGCACCAUCCGCAUGAGCUUCGUCAAAGGCUGGGGAGCGGAGUACAGGAGACAGACUGUG2000000006ACCAGUACCCCCUGCUGGAUUGAGCUGCACCUGAAUGGGCCUUUGCAGUGGCUUGACAAGGUCCUCACCCAGAUGGGCUCCCCAAGCAUCCGCUGUUCCAGUGUGUCUUAGAG2000000006ACAUCAAGUAUGGUAGGGGAGGGCAGGCUUGGGGAAAAUGGCCAUGCAGGAGGUGGAGAAAAUUGGA2000000006ACUCUACUCAACCCAUUGUUGUCAAGGAAGAAGAAAUCUUUCUCCCUCAACUGAAGGGGUGCACCCACCUGUUUUCUGAAACACACGAGCAAACCCAGAGGUGGAUGUUAUGA2000000006ACAGCUGUGUCUGCCAAACACAUUUACCCUUUGGCCCCACUUUG

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	557	653	722	823	1231	1344	1411	1524
Modification Positions	m6A	m6A	m6A	Y	m6A	m6A	m6A	m6A
Genomic Coordinates	15:67165346:+	15:67166836:+	15:67181241:+	15:67181342:+	15:67190426:+	15:67190539:+	15:67190606:+	15:67190719:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	bXBqJigD9oV3 f6YSioLdAWpr	bXBqJigD9oV3 f6YSioLdAWpr	bXBqJigD9oV3 f6YSioLdAWpr	bXBqJigD9oV3 f6YSioLdAWpr	bXBqJigD9oV3 f6YSioLdAWpr	3TeAZFYFxgvp 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U Lny8GcCeVGc9 UKen6WEino9G bXBqJigD9oV3 f6YSioLdAWpr	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb Ap2q43bQLNek jNkxUQNx8GRd msuJfBpJvM5H NjZ8bGGJsNSR QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn Lny8GcCeVGc9 bXBqJigD9oV3 f6YSioLdAWpr	3TeAZFYFxgvp 4HMi5ykupT9V 5aTkEfEpX8Xm 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U D6ncpa2PPWj3 BsCW7emuRX7M KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 LZJKems7W2wi PF5iqBNSbHaa UKen6WEino9G XUkp6ghERQML bXBqJigD9oV3 f6YSioLdAWpr Yfn77uLS5tv8