General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000557916
Gene ID:	ENSG00000137834
Gene Name:	SMAD6
Sequence (UNICHARACTER ENCODING)	AUGUUCAGGUCCAAACGCUCGGGGCUGGUGCGGCGACUUUGGCGAAGUCGUGUGGUCCCCGACCGGGAGGAAGGCGGCAGCGGCGGCGGCGGUGGCGGCGACGAGGAUGGGAGCUUGGGCAGCCGAGCUGAGCCGGCCCCGCGGGCAAGAGAGGGCGGAGGCUGCGGCCGCUCCGAAGUCCGCCCGGUAGCCCCGCGGCGGCCCCGGGЖCGCAGUGGGЖCAGCGAGGCGCCCAGGGCGCGGGGAGGCGCCGGCGCGCAGGGGGCCCCCCGAGGCCCAUGUCGGAGCCAGGGGCCGGCGCUGGGAGCUCCCUGCUGGЖCGUGGCGGAGCCGGGAGGCCCGGGCUGGCUGCCCGAGAGUGЖCUGCGAGACGGUGACCUGCUGUCUCUUUUCGGAGCGGGACGCCGCCGGCGCGCCCCGGGACGCCAGCGACCCCCUGGCCGGGGCGGCCCUGGAGCCGGCGGGCGGCGGGCGGAGUCGCGAAGCGCGCUCGCGGCUGCUGCUGCUGGAGCAGGAЖCUCAAAACCGUCACGUЖCUCGCUGCUGAAGCGGCUCAAGGAGCGCUCGCUGGЖCACGCUGCUGGAGGCGGUGGAGUCCCGCGGCGGCGUGCCGGGCGGCUGCGUGCUGGUGCCGCGCGCCGACCUCCGCCUGGGCGGCCAGCCCGCGCCGCCGCAGCUGCUGCUCGGCCGCCUCUUUCGCUGGCCCGACCUGCAGCACGCCGUGGAGCUGAAGCCCCUGUGCGGCUGCCACAGCUUCGCCGCCGCCGCCGACGGCCCUACCGUGUGCUGCAACCCCUACCACUUCAGCCGGCUCUGCGGGCCCGAAUCUCCGCCACCUCCCUACUCUCGGCUGUCUCCUCGCGACGAGUACAAGCCACUGGAUCUGUCCGAUUCCACAUUGUCUUACACUGAAACGGAGGCUACCAACUCCCUCAUCACUGCUCCGGGUGAAUUCUCAGCAGCAGAUGCUGGGAUAGGAAGCCGAGGGAACCGUGGUUUGGAGUCCUCUGUCCCCUGCAGUUAGAAGCUGGUCAUAGGGACCCCUACAUCCGGAGGAAUACCUGAAUCAAACUUUCCUUGAGAAAUGAGAGACGCCAGCAUGUCUCCGGACGCCACCAAGCCGAGCCACUGGUGCAGCGUGGCGUACUGGGAGCACCGGACGCGCGUGGGCCGCCUCUAUGCGGUGUACGACCAGGCCGUCAGCAUCUUCUACGACCUACCUCAGGGCAGCGGCUUCUGCCUGGGCCAGCUCAACCUGGAGCAGCGCAGCGAGUCGGUGCGGCGAACGCGCAGCAAGAUCGGCUUCGGCAPCCUGCUCAGCAAGGAGCCCGACGGCGUGUGGGCCUACAACCGCGGCGAGCACCCCAUCUUCGUCAACUCCCCGACGCUGGACGCGCCCGGCGGCCGC
Sequence (SHORT NAMES ENCODING)	AUGUUCAGGUCCAAACGCUCGGGGCUGGUGCGGCGACUUUGGCGAAGUCGUGUGGUCCCCGACCGGGAGGAAGGCGGCAGCGGCGGCGGCGGUGGCGGCGACGAGGAUGGGAGCUUGGGCAGCCGAGCUGAGCCGGCCCCGCGGGCAAGAGAGGGCGGAGGCUGCGGCCGCUCCGAAGUCCGCCCGGUAGCCCCGCGGCGGCCCCGGGm6ACGCAGUGGGm6ACAGCGAGGCGCCCAGGGCGCGGGGAGGCGCCGGCGCGCAGGGGGCCCCCCGAGGCCCAUGUCGGAGCCAGGGGCCGGCGCUGGGAGCUCCCUGCUGGm6ACGUGGCGGAGCCGGGAGGCCCGGGCUGGCUGCCCGAGAGUGm6ACUGCGAGACGGUGACCUGCUGUCUCUUUUCGGAGCGGGACGCCGCCGGCGCGCCCCGGGACGCCAGCGACCCCCUGGCCGGGGCGGCCCUGGAGCCGGCGGGCGGCGGGCGGAGUCGCGAAGCGCGCUCGCGGCUGCUGCUGCUGGAGCAGGAm6ACUCAAAACCGUCACGUm6ACUCGCUGCUGAAGCGGCUCAAGGAGCGCUCGCUGGm6ACACGCUGCUGGAGGCGGUGGAGUCCCGCGGCGGCGUGCCGGGCGGCUGCGUGCUGGUGCCGCGCGCCGACCUCCGCCUGGGCGGCCAGCCCGCGCCGCCGCAGCUGCUGCUCGGCCGCCUCUUUCGCUGGCCCGACCUGCAGCACGCCGUGGAGCUGAAGCCCCUGUGCGGCUGCCACAGCUUCGCCGCCGCCGCCGACGGCCCUACCGUGUGCUGCAACCCCUACCACUUCAGCCGGCUCUGCGGGCCCGAAUCUCCGCCACCUCCCUACUCUCGGCUGUCUCCUCGCGACGAGUACAAGCCACUGGAUCUGUCCGAUUCCACAUUGUCUUACACUGAAACGGAGGCUACCAACUCCCUCAUCACUGCUCCGGGUGAAUUCUCAGCAGCAGAUGCUGGGAUAGGAAGCCGAGGGAACCGUGGUUUGGAGUCCUCUGUCCCCUGCAGUUAGAAGCUGGUCAUAGGGACCCCUACAUCCGGAGGAAUACCUGAAUCAAACUUUCCUUGAGAAAUGAGAGACGCCAGCAUGUCUCCGGACGCCACCAAGCCGAGCCACUGGUGCAGCGUGGCGUACUGGGAGCACCGGACGCGCGUGGGCCGCCUCUAUGCGGUGUACGACCAGGCCGUCAGCAUCUUCUACGACCUACCUCAGGGCAGCGGCUUCUGCCUGGGCCAGCUCAACCUGGAGCAGCGCAGCGAGUCGGUGCGGCGAACGCGCAGCAAGAUCGGCUUCGGCAYCCUGCUCAGCAAGGAGCCCGACGGCGUGUGGGCCUACAACCGCGGCGAGCACCCCAUCUUCGUCAACUCCCCGACGCUGGACGCGCCCGGCGGCCGC
Sequence (MODOMICS CODE ENCODING)	AUGUUCAGGUCCAAACGCUCGGGGCUGGUGCGGCGACUUUGGCGAAGUCGUGUGGUCCCCGACCGGGAGGAAGGCGGCAGCGGCGGCGGCGGUGGCGGCGACGAGGAUGGGAGCUUGGGCAGCCGAGCUGAGCCGGCCCCGCGGGCAAGAGAGGGCGGAGGCUGCGGCCGCUCCGAAGUCCGCCCGGUAGCCCCGCGGCGGCCCCGGG2000000006ACGCAGUGGG2000000006ACAGCGAGGCGCCCAGGGCGCGGGGAGGCGCCGGCGCGCAGGGGGCCCCCCGAGGCCCAUGUCGGAGCCAGGGGCCGGCGCUGGGAGCUCCCUGCUGG2000000006ACGUGGCGGAGCCGGGAGGCCCGGGCUGGCUGCCCGAGAGUG2000000006ACUGCGAGACGGUGACCUGCUGUCUCUUUUCGGAGCGGGACGCCGCCGGCGCGCCCCGGGACGCCAGCGACCCCCUGGCCGGGGCGGCCCUGGAGCCGGCGGGCGGCGGGCGGAGUCGCGAAGCGCGCUCGCGGCUGCUGCUGCUGGAGCAGGA2000000006ACUCAAAACCGUCACGU2000000006ACUCGCUGCUGAAGCGGCUCAAGGAGCGCUCGCUGG2000000006ACACGCUGCUGGAGGCGGUGGAGUCCCGCGGCGGCGUGCCGGGCGGCUGCGUGCUGGUGCCGCGCGCCGACCUCCGCCUGGGCGGCCAGCCCGCGCCGCCGCAGCUGCUGCUCGGCCGCCUCUUUCGCUGGCCCGACCUGCAGCACGCCGUGGAGCUGAAGCCCCUGUGCGGCUGCCACAGCUUCGCCGCCGCCGCCGACGGCCCUACCGUGUGCUGCAACCCCUACCACUUCAGCCGGCUCUGCGGGCCCGAAUCUCCGCCACCUCCCUACUCUCGGCUGUCUCCUCGCGACGAGUACAAGCCACUGGAUCUGUCCGAUUCCACAUUGUCUUACACUGAAACGGAGGCUACCAACUCCCUCAUCACUGCUCCGGGUGAAUUCUCAGCAGCAGAUGCUGGGAUAGGAAGCCGAGGGAACCGUGGUUUGGAGUCCUCUGUCCCCUGCAGUUAGAAGCUGGUCAUAGGGACCCCUACAUCCGGAGGAAUACCUGAAUCAAACUUUCCUUGAGAAAUGAGAGACGCCAGCAUGUCUCCGGACGCCACCAAGCCGAGCCACUGGUGCAGCGUGGCGUACUGGGAGCACCGGACGCGCGUGGGCCGCCUCUAUGCGGUGUACGACCAGGCCGUCAGCAUCUUCUACGACCUACCUCAGGGCAGCGGCUUCUGCCUGGGCCAGCUCAACCUGGAGCAGCGCAGCGAGUCGGUGCGGCGAACGCGCAGCAAGAUCGGCUUCGGCA2000000009UCCUGCUCAGCAAGGAGCCCGACGGCGUGUGGGCCUACAACCGCGGCGAGCACCCCAUCUUCGUCAACUCCCCGACGCUGGACGCGCCCGGCGGCCGC

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	209	219	317	359	513	530	566	1304
Modification Positions	m6A	m6A	m6A	m6A	m6A	m6A	m6A	Y
Genomic Coordinates	15:66703467:+	15:66703477:+	15:66703575:+	15:66703617:+	15:66703771:+	15:66703788:+	15:66703824:+	15:66781216:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn	5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe QmcpiJ88DBDn QpiKdbVikVz2 V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn	3TeAZFYFxgvp 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn bXBqJigD9oV3	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn bXBqJigD9oV3 f6YSioLdAWpr	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn	bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Yfn77uLS5tv8