General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000258874
Gene ID:	ENSG00000136371
Gene Name:	MTHFS
Sequence (UNICHARACTER ENCODING)	GGGACUGGACUCGGCUUGGGCGUGAGAUGGCGGCGGCAGCGGUGAGCAGCGCCAAGCGGAGCCUGCGGGGAGAGCUGAAGCAGCGUCUGCGGGCGAUGAGUGCCGAGGAGCGGCUACGCCAGUCCCGCGUACUGAGCCAGAAGGUGAUUGCCCACAGUGAGUAUCAAAAGUCCAAAAGAAUUUCCAUCUUUCUGAGCAUGCAAGAUGAAAUUGAGACAGAAGAGAUCAUCAAGGЖCAUUUUCCAACGAGGCAAAAUCUGCUUCAPCCCUCGGUACCGGUUCCAGAGCAAUCACAUGGAUAUGGUGAGAAUAGAAUCACCAGAGGAAAUUUCUPUACUUCCCAAAACAPCCUGGAAUAUCCCUCAGCCUGGUGAGGGUGAUGUUCGGGAGGAGGCCUUGUCCACAGGGGGACUUGAUCUCAUCUUCAUGCCAGGCCUUGGGUUUGACAAACAUGGCAACCGACUGGGGAGGGGCAAGGGCUACUAUGAUGCCUAUCUGAAGCGCUGUUUGCAGCAUCAGGAAGUGAAGCCCUACACCCUGGCGUUGGCUUUCAAAGAЖCAGAUUUGCCUCCAGGUCCCAGUGAAUGAAAACGACAUGAAGGUAGAUGAAGUCCUPUACGAAGACUCGUCAACAGCUUAAAUCUGGAUUACUACAGCCAAAUAAUCAGUGUUUUAUAUGAGAGUAAAGCAAAGUAUGUGUAUUUUUCCCUUGUCAAAAAUUAGUUGAAAUUGUUCAUUAAUGUGAAUACAGACUGCAUUUUAAAAUUGUAAUUAUGAAAUACCUUAUЖUAAAACCAUCUPUAAAAACCAAUAGAAGUGUGAAUAGUAGAAUAUUAAUUAAAAUGGAGGCUAUCAGCCUGUGAUUUUCAGCUUAACUUCCUGGUGUUAAUGUGACAAGUUGAUCUGUCUACUUUGCAAUUUAAGUUAAAUAUUUAUGAGGAACUGUGCUCCGACUGAGUGCGAGAGGAAGGUAAACUUGCGGGAGUGGGCACUGUAUUUCAUUACGCCUUUCAUGACCUGGUCUGUCCUGGCAGGCACAUGGAGACUUGGGGACUAUUAAUUUAUUUGUUGGUAUUUGCUUUGGAUACAGAAUUCCCUAAGAAUAUUAUCUCACUUCAUCAUGACUUCCUUUACCCACUCUAGAAUUUUAUGUUGGACACUUUGUAGCUUUUGGUGGUUAGUGGAGGGAAACCUUUUAUGAUUUAAAUACUUUUACUCCACUGAUUGGUUACCAUCACUGCAUGUAUCAGCCCUUGAUGAGUUUAAGAUCUAGUAUCUUAUAAGUUAGAAAUUAUUUCUGUUUACUCAUGGUUUCUGCUUUGGAAAUGAAAUUUGCUGUGAGUUGAAAGUUGGCAGAUGGCAACACAGCUAGGGAGCAAUAAUUUUGUUGUGGGGAGGAUUUGGUCAUCUCCAGAAACCCGGGAGUCACGUGGCUCUCUUACUCACACUCCAUGUCCAUCCUGUCACCAGGUCUUGUUGAUUUUGCCUCUGAAAUGCCUCUUAAAUCUAUUCUCUCCUUUCAAUUUUCCUGUCACUCCUUUUGUCCAGCCUUUUAGCAUUUCUAAGCUGGACUAGGCGAGAGUGUCACACCUGCUUCCCUUGGCUUCCAUCUUGCCUCUUCCAGUUUAUUUCUCAAGCUGCAGUCAAACUGAUCUUAGAAAACACGAAUCUAAUCAUGCAGCACCCCUGACUAAGGUCUUCCGGUGGCUGUUCAGAGCCUCUUGGGUAGCAAACAGAUGGCUUCUGUUGUAUACAAAGCCCCUUAAGAGAGGUCUCCUCAUCUACUUUUUCUAGCCUCUUCUCUCCCAACUCUGUAUUCUCCUGUAACACUGACUGAGCACUGCAGGCUUCUGCCCUUUGCACAUAGUAAGCAUGCAUUUCUCUCUGUCUGAAAUGCUCUUUCUGUUGUUCAUCUAGAAGACUGUUUUCCCUUGAAGACUCAGCCCUAGCAUCACCUCUUCUGUGAAGUCUUCUGCUACUUUCCCAAGCAGAGUGAGUGUUCCUUCCCUUGUCUGAGUGGCCUUGGCCAUUGAUGUGCUUAUCAUGUUGUCUUACGUAUCAAAUUAUUUGUUGUCAUAUCUGUCCCCUUCACCAUACUGUGAGCUCCAAAGAAAAGAAGUGAUCUUUAUACUUCUUAUGCUUAGUACACAACUAGACAUAUAGUGUGUGUGUGAGAGAGAGAAUUUUUUAAUGAAAUAAUUGAAUACAUUGGAAGUGUUUCAUUCAAAAUACUCAUCCAUUAUUCUUUGGAUAGUAGCAUAAAUUUGAUGUUUUAUGUACAAAAGUAAAAACAUUUGAAAAAUA
Sequence (SHORT NAMES ENCODING)	GGGACUGGACUCGGCUUGGGCGUGAGAUGGCGGCGGCAGCGGUGAGCAGCGCCAAGCGGAGCCUGCGGGGAGAGCUGAAGCAGCGUCUGCGGGCGAUGAGUGCCGAGGAGCGGCUACGCCAGUCCCGCGUACUGAGCCAGAAGGUGAUUGCCCACAGUGAGUAUCAAAAGUCCAAAAGAAUUUCCAUCUUUCUGAGCAUGCAAGAUGAAAUUGAGACAGAAGAGAUCAUCAAGGm6ACAUUUUCCAACGAGGCAAAAUCUGCUUCAYCCCUCGGUACCGGUUCCAGAGCAAUCACAUGGAUAUGGUGAGAAUAGAAUCACCAGAGGAAAUUUCUYUACUUCCCAAAACAYCCUGGAAUAUCCCUCAGCCUGGUGAGGGUGAUGUUCGGGAGGAGGCCUUGUCCACAGGGGGACUUGAUCUCAUCUUCAUGCCAGGCCUUGGGUUUGACAAACAUGGCAACCGACUGGGGAGGGGCAAGGGCUACUAUGAUGCCUAUCUGAAGCGCUGUUUGCAGCAUCAGGAAGUGAAGCCCUACACCCUGGCGUUGGCUUUCAAAGAm6ACAGAUUUGCCUCCAGGUCCCAGUGAAUGAAAACGACAUGAAGGUAGAUGAAGUCCUYUACGAAGACUCGUCAACAGCUUAAAUCUGGAUUACUACAGCCAAAUAAUCAGUGUUUUAUAUGAGAGUAAAGCAAAGUAUGUGUAUUUUUCCCUUGUCAAAAAUUAGUUGAAAUUGUUCAUUAAUGUGAAUACAGACUGCAUUUUAAAAUUGUAAUUAUGAAAUACCUUAUm6AUAAAACCAUCUYUAAAAACCAAUAGAAGUGUGAAUAGUAGAAUAUUAAUUAAAAUGGAGGCUAUCAGCCUGUGAUUUUCAGCUUAACUUCCUGGUGUUAAUGUGACAAGUUGAUCUGUCUACUUUGCAAUUUAAGUUAAAUAUUUAUGAGGAACUGUGCUCCGACUGAGUGCGAGAGGAAGGUAAACUUGCGGGAGUGGGCACUGUAUUUCAUUACGCCUUUCAUGACCUGGUCUGUCCUGGCAGGCACAUGGAGACUUGGGGACUAUUAAUUUAUUUGUUGGUAUUUGCUUUGGAUACAGAAUUCCCUAAGAAUAUUAUCUCACUUCAUCAUGACUUCCUUUACCCACUCUAGAAUUUUAUGUUGGACACUUUGUAGCUUUUGGUGGUUAGUGGAGGGAAACCUUUUAUGAUUUAAAUACUUUUACUCCACUGAUUGGUUACCAUCACUGCAUGUAUCAGCCCUUGAUGAGUUUAAGAUCUAGUAUCUUAUAAGUUAGAAAUUAUUUCUGUUUACUCAUGGUUUCUGCUUUGGAAAUGAAAUUUGCUGUGAGUUGAAAGUUGGCAGAUGGCAACACAGCUAGGGAGCAAUAAUUUUGUUGUGGGGAGGAUUUGGUCAUCUCCAGAAACCCGGGAGUCACGUGGCUCUCUUACUCACACUCCAUGUCCAUCCUGUCACCAGGUCUUGUUGAUUUUGCCUCUGAAAUGCCUCUUAAAUCUAUUCUCUCCUUUCAAUUUUCCUGUCACUCCUUUUGUCCAGCCUUUUAGCAUUUCUAAGCUGGACUAGGCGAGAGUGUCACACCUGCUUCCCUUGGCUUCCAUCUUGCCUCUUCCAGUUUAUUUCUCAAGCUGCAGUCAAACUGAUCUUAGAAAACACGAAUCUAAUCAUGCAGCACCCCUGACUAAGGUCUUCCGGUGGCUGUUCAGAGCCUCUUGGGUAGCAAACAGAUGGCUUCUGUUGUAUACAAAGCCCCUUAAGAGAGGUCUCCUCAUCUACUUUUUCUAGCCUCUUCUCUCCCAACUCUGUAUUCUCCUGUAACACUGACUGAGCACUGCAGGCUUCUGCCCUUUGCACAUAGUAAGCAUGCAUUUCUCUCUGUCUGAAAUGCUCUUUCUGUUGUUCAUCUAGAAGACUGUUUUCCCUUGAAGACUCAGCCCUAGCAUCACCUCUUCUGUGAAGUCUUCUGCUACUUUCCCAAGCAGAGUGAGUGUUCCUUCCCUUGUCUGAGUGGCCUUGGCCAUUGAUGUGCUUAUCAUGUUGUCUUACGUAUCAAAUUAUUUGUUGUCAUAUCUGUCCCCUUCACCAUACUGUGAGCUCCAAAGAAAAGAAGUGAUCUUUAUACUUCUUAUGCUUAGUACACAACUAGACAUAUAGUGUGUGUGUGAGAGAGAGAAUUUUUUAAUGAAAUAAUUGAAUACAUUGGAAGUGUUUCAUUCAAAAUACUCAUCCAUUAUUCUUUGGAUAGUAGCAUAAAUUUGAUGUUUUAUGUACAAAAGUAAAAACAUUUGAAAAAUA
Sequence (MODOMICS CODE ENCODING)	GGGACUGGACUCGGCUUGGGCGUGAGAUGGCGGCGGCAGCGGUGAGCAGCGCCAAGCGGAGCCUGCGGGGAGAGCUGAAGCAGCGUCUGCGGGCGAUGAGUGCCGAGGAGCGGCUACGCCAGUCCCGCGUACUGAGCCAGAAGGUGAUUGCCCACAGUGAGUAUCAAAAGUCCAAAAGAAUUUCCAUCUUUCUGAGCAUGCAAGAUGAAAUUGAGACAGAAGAGAUCAUCAAGG2000000006ACAUUUUCCAACGAGGCAAAAUCUGCUUCA2000000009UCCCUCGGUACCGGUUCCAGAGCAAUCACAUGGAUAUGGUGAGAAUAGAAUCACCAGAGGAAAUUUCU2000000009UUACUUCCCAAAACA2000000009UCCUGGAAUAUCCCUCAGCCUGGUGAGGGUGAUGUUCGGGAGGAGGCCUUGUCCACAGGGGGACUUGAUCUCAUCUUCAUGCCAGGCCUUGGGUUUGACAAACAUGGCAACCGACUGGGGAGGGGCAAGGGCUACUAUGAUGCCUAUCUGAAGCGCUGUUUGCAGCAUCAGGAAGUGAAGCCCUACACCCUGGCGUUGGCUUUCAAAGA2000000006ACAGAUUUGCCUCCAGGUCCCAGUGAAUGAAAACGACAUGAAGGUAGAUGAAGUCCU2000000009UUACGAAGACUCGUCAACAGCUUAAAUCUGGAUUACUACAGCCAAAUAAUCAGUGUUUUAUAUGAGAGUAAAGCAAAGUAUGUGUAUUUUUCCCUUGUCAAAAAUUAGUUGAAAUUGUUCAUUAAUGUGAAUACAGACUGCAUUUUAAAAUUGUAAUUAUGAAAUACCUUAU2000000006AUAAAACCAUCU2000000009UUAAAAACCAAUAGAAGUGUGAAUAGUAGAAUAUUAAUUAAAAUGGAGGCUAUCAGCCUGUGAUUUUCAGCUUAACUUCCUGGUGUUAAUGUGACAAGUUGAUCUGUCUACUUUGCAAUUUAAGUUAAAUAUUUAUGAGGAACUGUGCUCCGACUGAGUGCGAGAGGAAGGUAAACUUGCGGGAGUGGGCACUGUAUUUCAUUACGCCUUUCAUGACCUGGUCUGUCCUGGCAGGCACAUGGAGACUUGGGGACUAUUAAUUUAUUUGUUGGUAUUUGCUUUGGAUACAGAAUUCCCUAAGAAUAUUAUCUCACUUCAUCAUGACUUCCUUUACCCACUCUAGAAUUUUAUGUUGGACACUUUGUAGCUUUUGGUGGUUAGUGGAGGGAAACCUUUUAUGAUUUAAAUACUUUUACUCCACUGAUUGGUUACCAUCACUGCAUGUAUCAGCCCUUGAUGAGUUUAAGAUCUAGUAUCUUAUAAGUUAGAAAUUAUUUCUGUUUACUCAUGGUUUCUGCUUUGGAAAUGAAAUUUGCUGUGAGUUGAAAGUUGGCAGAUGGCAACACAGCUAGGGAGCAAUAAUUUUGUUGUGGGGAGGAUUUGGUCAUCUCCAGAAACCCGGGAGUCACGUGGCUCUCUUACUCACACUCCAUGUCCAUCCUGUCACCAGGUCUUGUUGAUUUUGCCUCUGAAAUGCCUCUUAAAUCUAUUCUCUCCUUUCAAUUUUCCUGUCACUCCUUUUGUCCAGCCUUUUAGCAUUUCUAAGCUGGACUAGGCGAGAGUGUCACACCUGCUUCCCUUGGCUUCCAUCUUGCCUCUUCCAGUUUAUUUCUCAAGCUGCAGUCAAACUGAUCUUAGAAAACACGAAUCUAAUCAUGCAGCACCCCUGACUAAGGUCUUCCGGUGGCUGUUCAGAGCCUCUUGGGUAGCAAACAGAUGGCUUCUGUUGUAUACAAAGCCCCUUAAGAGAGGUCUCCUCAUCUACUUUUUCUAGCCUCUUCUCUCCCAACUCUGUAUUCUCCUGUAACACUGACUGAGCACUGCAGGCUUCUGCCCUUUGCACAUAGUAAGCAUGCAUUUCUCUCUGUCUGAAAUGCUCUUUCUGUUGUUCAUCUAGAAGACUGUUUUCCCUUGAAGACUCAGCCCUAGCAUCACCUCUUCUGUGAAGUCUUCUGCUACUUUCCCAAGCAGAGUGAGUGUUCCUUCCCUUGUCUGAGUGGCCUUGGCCAUUGAUGUGCUUAUCAUGUUGUCUUACGUAUCAAAUUAUUUGUUGUCAUAUCUGUCCCCUUCACCAUACUGUGAGCUCCAAAGAAAAGAAGUGAUCUUUAUACUUCUUAUGCUUAGUACACAACUAGACAUAUAGUGUGUGUGUGAGAGAGAGAAUUUUUUAAUGAAAUAAUUGAAUACAUUGGAAGUGUUUCAUUCAAAAUACUCAUCCAUUAUUCUUUGGAUAGUAGCAUAAAUUUGAUGUUUUAUGUACAAAAGUAAAAACAUUUGAAAAAUA

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	235	265	333	348	557	614	786	798
Modification Positions	m6A	Y	Y	Y	m6A	Y	m6A	Y
Genomic Coordinates	15:79889263:-	15:79889233:-	15:79889165:-	15:79889150:-	15:79845291:-	15:79845234:-	15:79845062:-	15:79845050:-
Level of Experimental Evidence	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	3TeAZFYFxgvp 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U D6ncpa2PPWj3 BsCW7emuRX7M Lny8GcCeVGc9 LZJKems7W2wi UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BsCW7emuRX7M Lny8GcCeVGc9 LZJKems7W2wi XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	834aFpha8RvT dA7YoLwHrzgR JASnTTw2HeNE ksEP666umrV9 ZuM5xpZmNuDL	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8