General Data

RNA Type	unknown
Original Source	Sci-ModoM
Transcript ID:	ENST00000586344
Gene ID:	ENSG00000031823
Gene Name:	RANBP3
Sequence (UNICHARACTER ENCODING)	AUUUUGCUUUUGGGUCAUUCACUGCUAGUGUUAGAAACACAAUCGAUUUUUGUAUAUUGAUCUUGUGUCCUGUAGCUUGACAAGGGGGUGAAGCUUAGCACAAACGCAGGGCUACCUCCAGGAGCCAUAAUGCCACAGUCUCUGUGCCUUGCCCAGGAACAGGCUUGCCUGCCUGAGUCACAGGCCUUUUAUGACAAUCCUUCCUGUUGUGGAUCAGAUUAGACCACCAUCCCCACUCCCUGUAUGGGCACAGUUGCCAAGACACACAGAUGAAGGGGUCCAUGUGGACAGGUGGCUGGGCGAGGCUGGGCUCUCGAGCCAUCCCAGGAGCUCGUGGGCAUUCACCUUUCCCUCUAGUUUUGUGAAUUUGUCAGCCCGGACUCUGGCCCAGGGGGAGCUGGCCUCCUCCACGGUGGCCAGGAGUGCCCCCUCACUGAGACGGGAAGCUCCGCAGGCACAUCUGGAAAGGGGAGGCAGGCUCACUGUGUGCCACCUUUGACCUUUUCAUCACAAAAACCUGUCUCACUUCCCAGACAUCUGUAGUGGUGCCAAGGUUCUUCCUGGCCACAGCCGCAUCCUCUGACAGACAAGCCUUCUAGGAAAGGGAAGUGGGGCCUGAGCGCCUGUGUUCCGUGGCUCCCUGACAUUCUCCAGAGCCAGGUACAGGGCCGCUGAGCAGCUCGGCUCCUGAGCCUGCAGCAGGUCAUAGACAGCUGGGAGGGCGGCUGACGCCCCACCUGCCCCCAUGGUCAGCAGCUGGCCCAAGAGCCAUCGUUCCUCCUGCCCUUGUCUCUCCCCUCCUCCAGGCGCCUUCCAGGCCUGCUGAUCGGACGAGACUUCUGUUGUAAUUUGGAAAUGUUCUCCCUGGUUCUCCAGGCCCGAAGUCACUGAGGCCAAGACCAUAGUCCUCUCCUGCCCUUGCCCCCCAGGCCCAGCCCCAGCCCAGGCAGGCCUGCUGUUGAUAUUUUGUCUUGUGCUUUUAGAGGAAAGGAGCAGUGGCUUCCGGUUGAAGCCACCAACGCUGAUCCACGGCCAAGCCCCCAGCGCAGGUCUGCCAAGCCAGAAGCCCAAGGAGCAGCAGCGGAGCGUGCUUCGCCCGGCAGUGUUACAAGCUCCGCAGCCAAAGGCGCUGUCCCAGACUGUCCCCAGCAGUGGCACCAACGGGGUCAGCCUCCCAGCAGACUGCACGGGGGCAGUGCCCGCAGCAUCCCCUGACACUGCUGCAUGGAGAAGUCCUUCCGAAGCUGCCGAUGAGGAGAAAGAGCCCCAGAAAAAUGAGUCCAGCAAUGCCUCUGAAGAGGAAGCCUGUGAGAAAAAAGACCCCGCCACACAGCAAGCCUUUGUAUUUGGGCAGAACUUGAGGGACAGAGUUAAGCUGAUAAAUGAGAGCGUGGACGAЖGCCGACAUGGAGAAUGCUGGACACCCCAGCGCAGACACGCCAACCGCAACGAACUAUUUCCUCCAGUAUAUCAGUUCCAGUUUAGAGAACUCAACCAAUAGUGCCGACGCCUCCAGCAACAAAUUUGUAUUUGGCCAGAACAUGAGCGAGCGAGUUUUGAGCCCCCCAAAAUUAAACGAGGUCAGUUCAGAUGCCAACAGGGAAAAUGCAGCUGCCGAGUCAGGGUCUGAGUCCUCGUCCCAGGAGGCCACCCCUGAGAAAGAGUCCCUGGCUGAGUCGGCAGCCGCCUACACCAAGGCAACAGCGCGGAAGUGUUUGUUGGAAAAAGUGGAAGUCAUCACCGGGGAGGAGGCGGAGAGCAAUGUGUUACAGAUGCAGUGCAAGCUGUUUGUCUUUGACAAGACCUCACAGUCCUGGGUGGAGAGAGGCCGGGGGCUGCUCAGACUCAAUGACAUGGCGUCCACCGAUGACGGCACACUACAGUCCCGACUAGUGAUGCGGACCCAGGGGAGCCUGCGACUGAUCCUCAACACCAAGCUGUGGGCCCAGAUGCAGAUCGACAAGGCCAGCGAGAAGAGCAUUCGCAUCACAGCCAUGGACACCGAGGACCAGGGCGUGAAGGUCUUCCUGAUCUCGGCCAGCUCCAAGGACACAGGUCAGUUGUAUGCAGCCCUGCACCACCGCAPCCUGGCCCUGCGCAGCCGCGUGGAGCAGGAGCAGGAGGCCAAGAUGCCCGCGCCUGAGCCUGGGGCAGCCCCAUCCAACGAGGAGGACGACAGCGACGAUGACGAUGUCCUGGCUCCUUCAGGGGCCACCGCЖGCUGGUGCUGGUGACGAAGGGGACGGGCAGACGACCGGGAGCACAUAGCGGCCGGGAGCCCGGCUGCACACCAGGCUGCUGCUUUGUCCGUCUAUCCACCCGCCCACCCGCCCCCACCCCACCGGCAGCGUCCAGGUGCGGGGCCGGGAACCACACACCCCACUGGGCCGGCCACAGUCUGGACCCGCACGUCCUGUUCAAAAGCAGACUCGGGAЖCUGCCUGAAUGUGGUUUGGGЖCACGAGЖCCUCAUCAUAUUGAUGAGCGAACAAACAAGAЖCAUUUCCUCCCUCCCCUCCUUUGAAUUGAAAUGGCACAUUAAGЖCUUGUCACGGCUUCUC
Sequence (SHORT NAMES ENCODING)	AUUUUGCUUUUGGGUCAUUCACUGCUAGUGUUAGAAACACAAUCGAUUUUUGUAUAUUGAUCUUGUGUCCUGUAGCUUGACAAGGGGGUGAAGCUUAGCACAAACGCAGGGCUACCUCCAGGAGCCAUAAUGCCACAGUCUCUGUGCCUUGCCCAGGAACAGGCUUGCCUGCCUGAGUCACAGGCCUUUUAUGACAAUCCUUCCUGUUGUGGAUCAGAUUAGACCACCAUCCCCACUCCCUGUAUGGGCACAGUUGCCAAGACACACAGAUGAAGGGGUCCAUGUGGACAGGUGGCUGGGCGAGGCUGGGCUCUCGAGCCAUCCCAGGAGCUCGUGGGCAUUCACCUUUCCCUCUAGUUUUGUGAAUUUGUCAGCCCGGACUCUGGCCCAGGGGGAGCUGGCCUCCUCCACGGUGGCCAGGAGUGCCCCCUCACUGAGACGGGAAGCUCCGCAGGCACAUCUGGAAAGGGGAGGCAGGCUCACUGUGUGCCACCUUUGACCUUUUCAUCACAAAAACCUGUCUCACUUCCCAGACAUCUGUAGUGGUGCCAAGGUUCUUCCUGGCCACAGCCGCAUCCUCUGACAGACAAGCCUUCUAGGAAAGGGAAGUGGGGCCUGAGCGCCUGUGUUCCGUGGCUCCCUGACAUUCUCCAGAGCCAGGUACAGGGCCGCUGAGCAGCUCGGCUCCUGAGCCUGCAGCAGGUCAUAGACAGCUGGGAGGGCGGCUGACGCCCCACCUGCCCCCAUGGUCAGCAGCUGGCCCAAGAGCCAUCGUUCCUCCUGCCCUUGUCUCUCCCCUCCUCCAGGCGCCUUCCAGGCCUGCUGAUCGGACGAGACUUCUGUUGUAAUUUGGAAAUGUUCUCCCUGGUUCUCCAGGCCCGAAGUCACUGAGGCCAAGACCAUAGUCCUCUCCUGCCCUUGCCCCCCAGGCCCAGCCCCAGCCCAGGCAGGCCUGCUGUUGAUAUUUUGUCUUGUGCUUUUAGAGGAAAGGAGCAGUGGCUUCCGGUUGAAGCCACCAACGCUGAUCCACGGCCAAGCCCCCAGCGCAGGUCUGCCAAGCCAGAAGCCCAAGGAGCAGCAGCGGAGCGUGCUUCGCCCGGCAGUGUUACAAGCUCCGCAGCCAAAGGCGCUGUCCCAGACUGUCCCCAGCAGUGGCACCAACGGGGUCAGCCUCCCAGCAGACUGCACGGGGGCAGUGCCCGCAGCAUCCCCUGACACUGCUGCAUGGAGAAGUCCUUCCGAAGCUGCCGAUGAGGAGAAAGAGCCCCAGAAAAAUGAGUCCAGCAAUGCCUCUGAAGAGGAAGCCUGUGAGAAAAAAGACCCCGCCACACAGCAAGCCUUUGUAUUUGGGCAGAACUUGAGGGACAGAGUUAAGCUGAUAAAUGAGAGCGUGGACGAm6AGCCGACAUGGAGAAUGCUGGACACCCCAGCGCAGACACGCCAACCGCAACGAACUAUUUCCUCCAGUAUAUCAGUUCCAGUUUAGAGAACUCAACCAAUAGUGCCGACGCCUCCAGCAACAAAUUUGUAUUUGGCCAGAACAUGAGCGAGCGAGUUUUGAGCCCCCCAAAAUUAAACGAGGUCAGUUCAGAUGCCAACAGGGAAAAUGCAGCUGCCGAGUCAGGGUCUGAGUCCUCGUCCCAGGAGGCCACCCCUGAGAAAGAGUCCCUGGCUGAGUCGGCAGCCGCCUACACCAAGGCAACAGCGCGGAAGUGUUUGUUGGAAAAAGUGGAAGUCAUCACCGGGGAGGAGGCGGAGAGCAAUGUGUUACAGAUGCAGUGCAAGCUGUUUGUCUUUGACAAGACCUCACAGUCCUGGGUGGAGAGAGGCCGGGGGCUGCUCAGACUCAAUGACAUGGCGUCCACCGAUGACGGCACACUACAGUCCCGACUAGUGAUGCGGACCCAGGGGAGCCUGCGACUGAUCCUCAACACCAAGCUGUGGGCCCAGAUGCAGAUCGACAAGGCCAGCGAGAAGAGCAUUCGCAUCACAGCCAUGGACACCGAGGACCAGGGCGUGAAGGUCUUCCUGAUCUCGGCCAGCUCCAAGGACACAGGUCAGUUGUAUGCAGCCCUGCACCACCGCAYCCUGGCCCUGCGCAGCCGCGUGGAGCAGGAGCAGGAGGCCAAGAUGCCCGCGCCUGAGCCUGGGGCAGCCCCAUCCAACGAGGAGGACGACAGCGACGAUGACGAUGUCCUGGCUCCUUCAGGGGCCACCGCm6AGCUGGUGCUGGUGACGAAGGGGACGGGCAGACGACCGGGAGCACAUAGCGGCCGGGAGCCCGGCUGCACACCAGGCUGCUGCUUUGUCCGUCUAUCCACCCGCCCACCCGCCCCCACCCCACCGGCAGCGUCCAGGUGCGGGGCCGGGAACCACACACCCCACUGGGCCGGCCACAGUCUGGACCCGCACGUCCUGUUCAAAAGCAGACUCGGGAm6ACUGCCUGAAUGUGGUUUGGGm6ACACGAGm6ACCUCAUCAUAUUGAUGAGCGAACAAACAAGAm6ACAUUUCCUCCCUCCCCUCCUUUGAAUUGAAAUGGCACAUUAAGm6ACUUGUCACGGCUUCUC
Sequence (MODOMICS CODE ENCODING)	AUUUUGCUUUUGGGUCAUUCACUGCUAGUGUUAGAAACACAAUCGAUUUUUGUAUAUUGAUCUUGUGUCCUGUAGCUUGACAAGGGGGUGAAGCUUAGCACAAACGCAGGGCUACCUCCAGGAGCCAUAAUGCCACAGUCUCUGUGCCUUGCCCAGGAACAGGCUUGCCUGCCUGAGUCACAGGCCUUUUAUGACAAUCCUUCCUGUUGUGGAUCAGAUUAGACCACCAUCCCCACUCCCUGUAUGGGCACAGUUGCCAAGACACACAGAUGAAGGGGUCCAUGUGGACAGGUGGCUGGGCGAGGCUGGGCUCUCGAGCCAUCCCAGGAGCUCGUGGGCAUUCACCUUUCCCUCUAGUUUUGUGAAUUUGUCAGCCCGGACUCUGGCCCAGGGGGAGCUGGCCUCCUCCACGGUGGCCAGGAGUGCCCCCUCACUGAGACGGGAAGCUCCGCAGGCACAUCUGGAAAGGGGAGGCAGGCUCACUGUGUGCCACCUUUGACCUUUUCAUCACAAAAACCUGUCUCACUUCCCAGACAUCUGUAGUGGUGCCAAGGUUCUUCCUGGCCACAGCCGCAUCCUCUGACAGACAAGCCUUCUAGGAAAGGGAAGUGGGGCCUGAGCGCCUGUGUUCCGUGGCUCCCUGACAUUCUCCAGAGCCAGGUACAGGGCCGCUGAGCAGCUCGGCUCCUGAGCCUGCAGCAGGUCAUAGACAGCUGGGAGGGCGGCUGACGCCCCACCUGCCCCCAUGGUCAGCAGCUGGCCCAAGAGCCAUCGUUCCUCCUGCCCUUGUCUCUCCCCUCCUCCAGGCGCCUUCCAGGCCUGCUGAUCGGACGAGACUUCUGUUGUAAUUUGGAAAUGUUCUCCCUGGUUCUCCAGGCCCGAAGUCACUGAGGCCAAGACCAUAGUCCUCUCCUGCCCUUGCCCCCCAGGCCCAGCCCCAGCCCAGGCAGGCCUGCUGUUGAUAUUUUGUCUUGUGCUUUUAGAGGAAAGGAGCAGUGGCUUCCGGUUGAAGCCACCAACGCUGAUCCACGGCCAAGCCCCCAGCGCAGGUCUGCCAAGCCAGAAGCCCAAGGAGCAGCAGCGGAGCGUGCUUCGCCCGGCAGUGUUACAAGCUCCGCAGCCAAAGGCGCUGUCCCAGACUGUCCCCAGCAGUGGCACCAACGGGGUCAGCCUCCCAGCAGACUGCACGGGGGCAGUGCCCGCAGCAUCCCCUGACACUGCUGCAUGGAGAAGUCCUUCCGAAGCUGCCGAUGAGGAGAAAGAGCCCCAGAAAAAUGAGUCCAGCAAUGCCUCUGAAGAGGAAGCCUGUGAGAAAAAAGACCCCGCCACACAGCAAGCCUUUGUAUUUGGGCAGAACUUGAGGGACAGAGUUAAGCUGAUAAAUGAGAGCGUGGACGA2000000006AGCCGACAUGGAGAAUGCUGGACACCCCAGCGCAGACACGCCAACCGCAACGAACUAUUUCCUCCAGUAUAUCAGUUCCAGUUUAGAGAACUCAACCAAUAGUGCCGACGCCUCCAGCAACAAAUUUGUAUUUGGCCAGAACAUGAGCGAGCGAGUUUUGAGCCCCCCAAAAUUAAACGAGGUCAGUUCAGAUGCCAACAGGGAAAAUGCAGCUGCCGAGUCAGGGUCUGAGUCCUCGUCCCAGGAGGCCACCCCUGAGAAAGAGUCCCUGGCUGAGUCGGCAGCCGCCUACACCAAGGCAACAGCGCGGAAGUGUUUGUUGGAAAAAGUGGAAGUCAUCACCGGGGAGGAGGCGGAGAGCAAUGUGUUACAGAUGCAGUGCAAGCUGUUUGUCUUUGACAAGACCUCACAGUCCUGGGUGGAGAGAGGCCGGGGGCUGCUCAGACUCAAUGACAUGGCGUCCACCGAUGACGGCACACUACAGUCCCGACUAGUGAUGCGGACCCAGGGGAGCCUGCGACUGAUCCUCAACACCAAGCUGUGGGCCCAGAUGCAGAUCGACAAGGCCAGCGAGAAGAGCAUUCGCAUCACAGCCAUGGACACCGAGGACCAGGGCGUGAAGGUCUUCCUGAUCUCGGCCAGCUCCAAGGACACAGGUCAGUUGUAUGCAGCCCUGCACCACCGCA2000000009UCCUGGCCCUGCGCAGCCGCGUGGAGCAGGAGCAGGAGGCCAAGAUGCCCGCGCCUGAGCCUGGGGCAGCCCCAUCCAACGAGGAGGACGACAGCGACGAUGACGAUGUCCUGGCUCCUUCAGGGGCCACCGC2000000006AGCUGGUGCUGGUGACGAAGGGGACGGGCAGACGACCGGGAGCACAUAGCGGCCGGGAGCCCGGCUGCACACCAGGCUGCUGCUUUGUCCGUCUAUCCACCCGCCCACCCGCCCCCACCCCACCGGCAGCGUCCAGGUGCGGGGCCGGGAACCACACACCCCACUGGGCCGGCCACAGUCUGGACCCGCACGUCCUGUUCAAAAGCAGACUCGGGA2000000006ACUGCCUGAAUGUGGUUUGGG2000000006ACACGAG2000000006ACCUCAUCAUAUUGAUGAGCGAACAAACAAGA2000000006ACAUUUCCUCCCUCCCCUCCUUUGAAUUGAAAUGGCACAUUAAG2000000006ACUUGUCACGGCUUCUC

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	1399	2085	2218	2434	2455	2462	2494	2538
Modification Positions	m6A	Y	m6A	m6A	m6A	m6A	m6A	m6A
Genomic Coordinates	19:5925714:-	19:5917931:-	19:5917798:-	19:5917442:-	19:5917421:-	19:5917414:-	19:5917382:-	19:5917338:-
Level of Experimental Evidence	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	834aFpha8RvT dA7YoLwHrzgR ksEP666umrV9 ZuM5xpZmNuDL	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	834aFpha8RvT dA7YoLwHrzgR JASnTTw2HeNE ksEP666umrV9 ZuM5xpZmNuDL	3TeAZFYFxgvp 4HMi5ykupT9V 5aTkEfEpX8Xm 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn Lny8GcCeVGc9 UKen6WEino9G BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp 4HMi5ykupT9V 5aTkEfEpX8Xm 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn D6ncpa2PPWj3 8cMbzB4aD5Se BsCW7emuRX7M KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 LZJKems7W2wi PF5iqBNSbHaa UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn D6ncpa2PPWj3 KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 PF5iqBNSbHaa UKen6WEino9G BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp 4HMi5ykupT9V 5aTkEfEpX8Xm 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U 8cMbzB4aD5Se WiQcrNTGZHPT KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 PF5iqBNSbHaa UKen6WEino9G BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8