General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000600938
Gene ID:	ENSG00000077463
Gene Name:	SIRT6
Sequence (UNICHARACTER ENCODING)	UUЖUUGUUCCCGUGGGGCAGUCGAGGAUGUCGGUGAAUUACGCGGCGGGGCUGUCGCCGUACGCGGACAAGGGCAAGUGCGGCCUCCCGGAGGGGUCCCCACGGAGUCUGGACCAUGGAGGAGCGAGGUCUGGCCCCCAAGUUCGACACCACCUUUGAGAGCGCGCGGCCCACGCAGACCCACAUGGCGCUGGUGCAGCUGGAGCGCGUGGGCCUCCUCCGCUUCCUGGUCAGCCAGAACGUGGACGGGCUCCAUGUGCGCUCAGGCUUCCCCAGGGACAAACUGGCAGAGCUCCACGGGAACAUGUUUGUGGAAGAAUGUGCCAAGUGUAAGACGCAGUACGUCCGAGACACAGUCGUGGGCACCAUGGGCCUGAAGGCCACGGGCCGGCUCUGCACCGUGGCUAAGGCAAGGGGGCUGCGAGCCUGCAGGGGAGAGCUGAGGGACACCAPCCUAGACUGGGAGGACUCCCUGCCCGACCGGGACCUGGCACUCGCCGAUGAGGCCAGCAGGAACGCCGACCUGUCCAUCACGCUGGGUACAUCGCUGCAGAUCCGGCCCAGCGGGAACCUGCCGCUGGCUACCAAGCGCCGGGGAGGCCGCCUGGUCAUCGUCAACCUGCAGCCCACCAAGCACGACCGCCAUGCUGACCUCCGCAPCCAUGGCUACGUUGACGAGGUCAUGACCCGGCUCAUGAAGCACCUGGGGCUGGAGAUCCCCGCCUGGGACGGCCCCCGUGUGCUGGAGAGGGCGCUGCCACCCCUGCCCCGCCCGCCCACCCCCAAGCUGGAGCCCAAGGAGGAAUCUCCCACCCGGAUCAACGGCUCUAUCCCCGCCGGCCCCAAGCAGGAGCCCUGCGCCCAGCACAACGGCUCAGAGCCCGCCAGCCCCAAACGGGAGCGGCCCACCAGCCCUGCCCCCCACAGACCCCCCAAAAGGGUGAAGGCCAAGGCGGUCCCCAGCUGACCAGGGUGCUUGGGGAGGGUGGGGCUUUUUGUAGAAЖCUGUGGAUUCUUUUUCUCUCGUGGUCUCACUUUGUUACUUGUUUCUGUCCCCGGGAGCCUCAGGGCUCUGAGAGCUGUGCUCCAGGCCAGGGGUUACACCUGCCCUCCGUGGUCCCUCCCUGGGCUCCAGGGGCCUCUGGUGCGGUUCCGGGAAGAAGCCACACCCCAGAGGUGACAGGUGAGCCCCUGCCACACCCCAGCCUCUGACUUGCUGUGUUGUCCAGAGGUGAGGCUGGGCCCUCCCUGGUCUCCAGCUUAAЖCAGGAGUGAЖCUCCCUCUGUCCCCAGGGCCUCCCUUCUGGGCCCCCUACAGCCCACCCUACCCCPCCUCCAUGGGCCCUGCЖGGAGGGGAGЖCCCACCUUGAAGUGGGGGAUCAGUAGAGGCUUGCACUGCCUUUGGGGCUGGAGGGAGACGUGGGUCCACCAGGCUUCUGGAAAAGUCCUCAAUGCAAUAAAAACAAUUUCUUUCUUGC
Sequence (SHORT NAMES ENCODING)	UUm6AUUGUUCCCGUGGGGCAGUCGAGGAUGUCGGUGAAUUACGCGGCGGGGCUGUCGCCGUACGCGGACAAGGGCAAGUGCGGCCUCCCGGAGGGGUCCCCACGGAGUCUGGACCAUGGAGGAGCGAGGUCUGGCCCCCAAGUUCGACACCACCUUUGAGAGCGCGCGGCCCACGCAGACCCACAUGGCGCUGGUGCAGCUGGAGCGCGUGGGCCUCCUCCGCUUCCUGGUCAGCCAGAACGUGGACGGGCUCCAUGUGCGCUCAGGCUUCCCCAGGGACAAACUGGCAGAGCUCCACGGGAACAUGUUUGUGGAAGAAUGUGCCAAGUGUAAGACGCAGUACGUCCGAGACACAGUCGUGGGCACCAUGGGCCUGAAGGCCACGGGCCGGCUCUGCACCGUGGCUAAGGCAAGGGGGCUGCGAGCCUGCAGGGGAGAGCUGAGGGACACCAYCCUAGACUGGGAGGACUCCCUGCCCGACCGGGACCUGGCACUCGCCGAUGAGGCCAGCAGGAACGCCGACCUGUCCAUCACGCUGGGUACAUCGCUGCAGAUCCGGCCCAGCGGGAACCUGCCGCUGGCUACCAAGCGCCGGGGAGGCCGCCUGGUCAUCGUCAACCUGCAGCCCACCAAGCACGACCGCCAUGCUGACCUCCGCAYCCAUGGCUACGUUGACGAGGUCAUGACCCGGCUCAUGAAGCACCUGGGGCUGGAGAUCCCCGCCUGGGACGGCCCCCGUGUGCUGGAGAGGGCGCUGCCACCCCUGCCCCGCCCGCCCACCCCCAAGCUGGAGCCCAAGGAGGAAUCUCCCACCCGGAUCAACGGCUCUAUCCCCGCCGGCCCCAAGCAGGAGCCCUGCGCCCAGCACAACGGCUCAGAGCCCGCCAGCCCCAAACGGGAGCGGCCCACCAGCCCUGCCCCCCACAGACCCCCCAAAAGGGUGAAGGCCAAGGCGGUCCCCAGCUGACCAGGGUGCUUGGGGAGGGUGGGGCUUUUUGUAGAAm6ACUGUGGAUUCUUUUUCUCUCGUGGUCUCACUUUGUUACUUGUUUCUGUCCCCGGGAGCCUCAGGGCUCUGAGAGCUGUGCUCCAGGCCAGGGGUUACACCUGCCCUCCGUGGUCCCUCCCUGGGCUCCAGGGGCCUCUGGUGCGGUUCCGGGAAGAAGCCACACCCCAGAGGUGACAGGUGAGCCCCUGCCACACCCCAGCCUCUGACUUGCUGUGUUGUCCAGAGGUGAGGCUGGGCCCUCCCUGGUCUCCAGCUUAAm6ACAGGAGUGAm6ACUCCCUCUGUCCCCAGGGCCUCCCUUCUGGGCCCCCUACAGCCCACCCUACCCCYCCUCCAUGGGCCCUGCm6AGGAGGGGAGm6ACCCACCUUGAAGUGGGGGAUCAGUAGAGGCUUGCACUGCCUUUGGGGCUGGAGGGAGACGUGGGUCCACCAGGCUUCUGGAAAAGUCCUCAAUGCAAUAAAAACAAUUUCUUUCUUGC
Sequence (MODOMICS CODE ENCODING)	UU2000000006AUUGUUCCCGUGGGGCAGUCGAGGAUGUCGGUGAAUUACGCGGCGGGGCUGUCGCCGUACGCGGACAAGGGCAAGUGCGGCCUCCCGGAGGGGUCCCCACGGAGUCUGGACCAUGGAGGAGCGAGGUCUGGCCCCCAAGUUCGACACCACCUUUGAGAGCGCGCGGCCCACGCAGACCCACAUGGCGCUGGUGCAGCUGGAGCGCGUGGGCCUCCUCCGCUUCCUGGUCAGCCAGAACGUGGACGGGCUCCAUGUGCGCUCAGGCUUCCCCAGGGACAAACUGGCAGAGCUCCACGGGAACAUGUUUGUGGAAGAAUGUGCCAAGUGUAAGACGCAGUACGUCCGAGACACAGUCGUGGGCACCAUGGGCCUGAAGGCCACGGGCCGGCUCUGCACCGUGGCUAAGGCAAGGGGGCUGCGAGCCUGCAGGGGAGAGCUGAGGGACACCA2000000009UCCUAGACUGGGAGGACUCCCUGCCCGACCGGGACCUGGCACUCGCCGAUGAGGCCAGCAGGAACGCCGACCUGUCCAUCACGCUGGGUACAUCGCUGCAGAUCCGGCCCAGCGGGAACCUGCCGCUGGCUACCAAGCGCCGGGGAGGCCGCCUGGUCAUCGUCAACCUGCAGCCCACCAAGCACGACCGCCAUGCUGACCUCCGCA2000000009UCCAUGGCUACGUUGACGAGGUCAUGACCCGGCUCAUGAAGCACCUGGGGCUGGAGAUCCCCGCCUGGGACGGCCCCCGUGUGCUGGAGAGGGCGCUGCCACCCCUGCCCCGCCCGCCCACCCCCAAGCUGGAGCCCAAGGAGGAAUCUCCCACCCGGAUCAACGGCUCUAUCCCCGCCGGCCCCAAGCAGGAGCCCUGCGCCCAGCACAACGGCUCAGAGCCCGCCAGCCCCAAACGGGAGCGGCCCACCAGCCCUGCCCCCCACAGACCCCCCAAAAGGGUGAAGGCCAAGGCGGUCCCCAGCUGACCAGGGUGCUUGGGGAGGGUGGGGCUUUUUGUAGAA2000000006ACUGUGGAUUCUUUUUCUCUCGUGGUCUCACUUUGUUACUUGUUUCUGUCCCCGGGAGCCUCAGGGCUCUGAGAGCUGUGCUCCAGGCCAGGGGUUACACCUGCCCUCCGUGGUCCCUCCCUGGGCUCCAGGGGCCUCUGGUGCGGUUCCGGGAAGAAGCCACACCCCAGAGGUGACAGGUGAGCCCCUGCCACACCCCAGCCUCUGACUUGCUGUGUUGUCCAGAGGUGAGGCUGGGCCCUCCCUGGUCUCCAGCUUAA2000000006ACAGGAGUGA2000000006ACUCCCUCUGUCCCCAGGGCCUCCCUUCUGGGCCCCCUACAGCCCACCCUACCCC2000000009UCCUCCAUGGGCCCUGC2000000006AGGAGGGGAG2000000006ACCCACCUUGAAGUGGGGGAUCAGUAGAGGCUUGCACUGCCUUUGGGGCUGGAGGGAGACGUGGGUCCACCAGGCUUCUGGAAAAGUCCUCAAUGCAAUAAAAACAAUUUCUUUCUUGC

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	3	452	659	1003	1263	1273	1328	1345	1355
Modification Positions	m6A	Y	Y	m6A	m6A	m6A	Y	m6A	m6A
Genomic Coordinates	19:4182563:-	19:4175740:-	19:4174924:-	19:4174580:-	19:4174320:-	19:4174310:-	19:4174255:-	19:4174238:-	19:4174228:-
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	5Nnepx5V7yHo 6UuHp6YApVKv aHkqKEJkRYyb jNkxUQNx8GRd msuJfBpJvM5H	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP JkWoGWVwjNda Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP JkWoGWVwjNda Yfn77uLS5tv8	6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn UKen6WEino9G BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP JkWoGWVwjNda Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP iezFbUdmY3A6 JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp aivdrAsbdKEU gZuvgwMuBfgh msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QpiKdbVikVz2 VL7zkHvkfkoB VyCX26p5UBRL ArijeGVTwYBw BkoLW2CBToyL BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	dA7YoLwHrzgR ksEP666umrV9	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8