General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000537841
Gene ID:	ENSG00000256269
Gene Name:	HMBS
Sequence (UNICHARACTER ENCODING)	GACGCGAGGCUCUGCGGAGACCAGGAGUCAGACUGUAGGACGACCUCGGGUCCCACGUGUCCCCGGUACUCGCCGGCCGGAGCCCCCGGCUUCCCGGGGCCGGGGGACCUUA#CGGCACCCACACACAGCCUACUUUCCAAGCGGAGCCAUGUCUGGUAACGGCAAUGCGGCUGCAACGGCGGUGAGUGCUGAGCCGGUGACCAGCACACUUUGGGCUUCUGGACGAGCCGUGCAGCGAUUGGCCCCAGGUUGCCAUCCUCAGUCGUCUAUUGGAAGAAAACAGCCCAAAGAUGAGAGUGAUUCGCGUGGGUACCCGCAAGAGCCAGCUUGCUCGCAUACAGACGGACAGUGUGGUGGCAACAUUGAAAGCCUCGUACCCUGGCCUGCAGUUUGAAAUCAUUGCUAUGUCCACCACAGGGGACAAGAUUCUUGAUACUGCACUCUCUAAGAUUGGAGAGAAAAGCCUGUUUACCAAGGAGCUUGAACAUGCCCUGGAGAAGAAUGAAGUGGACCUGGUUGUUCACUCCUUGAAGGACCUGCCCACUGUGCUUCCPCCUGGCUUCACCAUCGGAGCCAUCUGCAAGCGGGAAAACCCUCAUGAUGCUGUUGUCUUUCACCCAAAAUUUGUUGGGAAGACCCUAGAAACCCUGCCAGAGAAGAGUGUGGUGGGAACCAGCUCCCUGCGAAGAGCAGCCCAGCUGCAGAGAAAGUUCCCGCAUCUGGAGUUCAGGAGUAUUCGGGGAAACCUCAACЖCCCGGCUUCGGAAGCUGGACGAGCAGCAGGAGUUCAGUGCCAUCAPCCUGGCAACAGCUGGCCUGCAGCGCAUGGGCUGGCACAACCGGGUGGGGCAGAUCCUGCACCCUGAGGAAUGCAUGUAUGCUGUGGGCCAGGGGGCCUUGGGCGUGGAAGUGCGAGCCAAGGACCAGGACAUCUUGGAUCUGGUGGGUGUGCUGCACGAUCCCGAGACUCUGCUUCGCUGCAUCGCUGAAAGGGCCUUCCUGAGGCACCUGGAAGGAGGCUGCAGUGUGCCAGUAGCCGUGCAUACAGCUAUGAAGGAUGGGCAACUGUACCUGACUGGAGGAGUCUGGAGUCUAGACGGCUCAGAUAGCAUACAAGAGACCAUGCAGGCUACCAPCCAUGUCCCUGCCCAGCAUGAAGAUGGCCCUGAGGAUGACCCACAGUUGGUAGGCAUCACUGCUCGUAЖCAUUCCACGAGGGCCCCAGUUGGCUGCCCAGAACUUGGGCAUCAGCCUGGCCAACUUGUUGCUGAGCAAAGGAGCCAAAAACAPCCUGGAUGUUGCACGGCAGCUUAACGAUGCCCAUUAЖCUGGUUUGUGGGGCACAGAUGCCUGGGUUGCUGCUGUCCAGUGCCUACAPCCCGGGCCUCAGUGCCCCAUUCUCACUGCUAUCUGGGGAGUGAUUACCCCGGGAGACUGAЖCUGCAGGGUUCAAGCCUUCCAGGGAUPUGCCUCACCUUGGGGCCUUGAUGACUGCCUUGCCUCCUCAGUAUGUGGGGGCUUCAUCUCUPUAGAGAAGUCCAAGCAACAGCCUUUGAAUGUAA
Sequence (SHORT NAMES ENCODING)	GACGCGAGGCUCUGCGGAGACCAGGAGUCAGACUGUAGGACGACCUCGGGUCCCACGUGUCCCCGGUACUCGCCGGCCGGAGCCCCCGGCUUCCCGGGGCCGGGGGACCUUAGmCGGCACCCACACACAGCCUACUUUCCAAGCGGAGCCAUGUCUGGUAACGGCAAUGCGGCUGCAACGGCGGUGAGUGCUGAGCCGGUGACCAGCACACUUUGGGCUUCUGGACGAGCCGUGCAGCGAUUGGCCCCAGGUUGCCAUCCUCAGUCGUCUAUUGGAAGAAAACAGCCCAAAGAUGAGAGUGAUUCGCGUGGGUACCCGCAAGAGCCAGCUUGCUCGCAUACAGACGGACAGUGUGGUGGCAACAUUGAAAGCCUCGUACCCUGGCCUGCAGUUUGAAAUCAUUGCUAUGUCCACCACAGGGGACAAGAUUCUUGAUACUGCACUCUCUAAGAUUGGAGAGAAAAGCCUGUUUACCAAGGAGCUUGAACAUGCCCUGGAGAAGAAUGAAGUGGACCUGGUUGUUCACUCCUUGAAGGACCUGCCCACUGUGCUUCCYCCUGGCUUCACCAUCGGAGCCAUCUGCAAGCGGGAAAACCCUCAUGAUGCUGUUGUCUUUCACCCAAAAUUUGUUGGGAAGACCCUAGAAACCCUGCCAGAGAAGAGUGUGGUGGGAACCAGCUCCCUGCGAAGAGCAGCCCAGCUGCAGAGAAAGUUCCCGCAUCUGGAGUUCAGGAGUAUUCGGGGAAACCUCAACm6ACCCGGCUUCGGAAGCUGGACGAGCAGCAGGAGUUCAGUGCCAUCAYCCUGGCAACAGCUGGCCUGCAGCGCAUGGGCUGGCACAACCGGGUGGGGCAGAUCCUGCACCCUGAGGAAUGCAUGUAUGCUGUGGGCCAGGGGGCCUUGGGCGUGGAAGUGCGAGCCAAGGACCAGGACAUCUUGGAUCUGGUGGGUGUGCUGCACGAUCCCGAGACUCUGCUUCGCUGCAUCGCUGAAAGGGCCUUCCUGAGGCACCUGGAAGGAGGCUGCAGUGUGCCAGUAGCCGUGCAUACAGCUAUGAAGGAUGGGCAACUGUACCUGACUGGAGGAGUCUGGAGUCUAGACGGCUCAGAUAGCAUACAAGAGACCAUGCAGGCUACCAYCCAUGUCCCUGCCCAGCAUGAAGAUGGCCCUGAGGAUGACCCACAGUUGGUAGGCAUCACUGCUCGUAm6ACAUUCCACGAGGGCCCCAGUUGGCUGCCCAGAACUUGGGCAUCAGCCUGGCCAACUUGUUGCUGAGCAAAGGAGCCAAAAACAYCCUGGAUGUUGCACGGCAGCUUAACGAUGCCCAUUAm6ACUGGUUUGUGGGGCACAGAUGCCUGGGUUGCUGCUGUCCAGUGCCUACAYCCCGGGCCUCAGUGCCCCAUUCUCACUGCUAUCUGGGGAGUGAUUACCCCGGGAGACUGAm6ACUGCAGGGUUCAAGCCUUCCAGGGAUYUGCCUCACCUUGGGGCCUUGAUGACUGCCUUGCCUCCUCAGUAUGUGGGGGCUUCAUCUCUYUAGAGAAGUCCAAGCAACAGCCUUUGAAUGUAA
Sequence (MODOMICS CODE ENCODING)	GACGCGAGGCUCUGCGGAGACCAGGAGUCAGACUGUAGGACGACCUCGGGUCCCACGUGUCCCCGGUACUCGCCGGCCGGAGCCCCCGGCUUCCCGGGGCCGGGGGACCUUA2000000090GCGGCACCCACACACAGCCUACUUUCCAAGCGGAGCCAUGUCUGGUAACGGCAAUGCGGCUGCAACGGCGGUGAGUGCUGAGCCGGUGACCAGCACACUUUGGGCUUCUGGACGAGCCGUGCAGCGAUUGGCCCCAGGUUGCCAUCCUCAGUCGUCUAUUGGAAGAAAACAGCCCAAAGAUGAGAGUGAUUCGCGUGGGUACCCGCAAGAGCCAGCUUGCUCGCAUACAGACGGACAGUGUGGUGGCAACAUUGAAAGCCUCGUACCCUGGCCUGCAGUUUGAAAUCAUUGCUAUGUCCACCACAGGGGACAAGAUUCUUGAUACUGCACUCUCUAAGAUUGGAGAGAAAAGCCUGUUUACCAAGGAGCUUGAACAUGCCCUGGAGAAGAAUGAAGUGGACCUGGUUGUUCACUCCUUGAAGGACCUGCCCACUGUGCUUCC2000000009UCCUGGCUUCACCAUCGGAGCCAUCUGCAAGCGGGAAAACCCUCAUGAUGCUGUUGUCUUUCACCCAAAAUUUGUUGGGAAGACCCUAGAAACCCUGCCAGAGAAGAGUGUGGUGGGAACCAGCUCCCUGCGAAGAGCAGCCCAGCUGCAGAGAAAGUUCCCGCAUCUGGAGUUCAGGAGUAUUCGGGGAAACCUCAAC2000000006ACCCGGCUUCGGAAGCUGGACGAGCAGCAGGAGUUCAGUGCCAUCA2000000009UCCUGGCAACAGCUGGCCUGCAGCGCAUGGGCUGGCACAACCGGGUGGGGCAGAUCCUGCACCCUGAGGAAUGCAUGUAUGCUGUGGGCCAGGGGGCCUUGGGCGUGGAAGUGCGAGCCAAGGACCAGGACAUCUUGGAUCUGGUGGGUGUGCUGCACGAUCCCGAGACUCUGCUUCGCUGCAUCGCUGAAAGGGCCUUCCUGAGGCACCUGGAAGGAGGCUGCAGUGUGCCAGUAGCCGUGCAUACAGCUAUGAAGGAUGGGCAACUGUACCUGACUGGAGGAGUCUGGAGUCUAGACGGCUCAGAUAGCAUACAAGAGACCAUGCAGGCUACCA2000000009UCCAUGUCCCUGCCCAGCAUGAAGAUGGCCCUGAGGAUGACCCACAGUUGGUAGGCAUCACUGCUCGUA2000000006ACAUUCCACGAGGGCCCCAGUUGGCUGCCCAGAACUUGGGCAUCAGCCUGGCCAACUUGUUGCUGAGCAAAGGAGCCAAAAACA2000000009UCCUGGAUGUUGCACGGCAGCUUAACGAUGCCCAUUA2000000006ACUGGUUUGUGGGGCACAGAUGCCUGGGUUGCUGCUGUCCAGUGCCUACA2000000009UCCCGGGCCUCAGUGCCCCAUUCUCACUGCUAUCUGGGGAGUGAUUACCCCGGGAGACUGA2000000006ACUGCAGGGUUCAAGCCUUCCAGGGAU2000000009UUGCCUCACCUUGGGGCCUUGAUGACUGCCUUGCCUCCUCAGUAUGUGGGGGCUUCAUCUCU2000000009UUAGAGAAGUCCAAGCAACAGCCUUUGAAUGUAA

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	113	555	754	800	1136	1205	1289	1326	1376	1437	1464	1526
Modification Positions	Gm	Y	m6A	Y	Y	m6A	Y	m6A	Y	m6A	Y	Y
Genomic Coordinates	11:119084997:+	11:119089731:+	11:119091428:+	11:119091474:+	11:119093005:+	11:119093162:+	11:119093246:+	11:119093283:+	11:119093333:+	11:119093394:+	11:119093421:+	11:119093483:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	jaSvBXBkn3xs YkSG92k4EHDM	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	834aFpha8RvT dA7YoLwHrzgR ksEP666umrV9 ZuM5xpZmNuDL	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp 4HMi5ykupT9V 5aTkEfEpX8Xm 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BsCW7emuRX7M KjeH7Nsffuas Lny8GcCeVGc9 LZJKems7W2wi UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd Mg9GixDBFQAT msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BsCW7emuRX7M Lny8GcCeVGc9 LZJKems7W2wi UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8