General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000308807
Gene ID:	ENSG00000168404
Gene Name:	MLKL
Sequence (UNICHARACTER ENCODING)	GUGAGCCUGGUGGUUGGCAGCUGGAGCCACGUCGGAGGGGGAAGUGUCGCAGCAUUCUCUGCAGGCAUCACAGACCUGAGGCAGUGGCCUCCGGAGGGCACUGGACAGAAACAGCCAUCCAAGUGGCUGAGUGGAGGGACCCUGCUCAAGUGCAGCUGCAGUGGCCGGGGUUUCCCUCAGGUAGGGAUCGGGGCGCCUUGUCGCCGCCAGCCACGUGUGGCGUCCGGUACAGUCAGCAGAGUGCAGGGUGCGGGCACCAGGAAAGGGGGCGCAGGGGAACUCCCGCGGGCCUCGCGUUUGCAAACUUCUCGCCUGGGCAGGAGGCGGUCGUGGGAAAGAAGGUGGAAGAGCGAGCUUUUUGGAACUGUGCACGGGACAGAUUGGACGCACACCCCUCGGGAGGCGCGAAGGCAUGGAAAAUUUGAAGCAUAUUAUCACCCUUGGCCAGGUCAUCCACAAACGGUGUGAAGAGAUGAAAUACUGCAAGAAACAGUGCCGGCGCCUGGGCCACCGCGUCCUCGGCCUGAUCAAGCCUCUGGAGAUGCUCCAGGACCAAGGAAAGAGGAGCGUGCCCUCUGAGAAGUUAACCACAGCCAUGAACCGCUUCAAGGCUGCCCUGGAGGAGGCUAAUGGGGAGAUAGAAAAGUUCAGCAAUAGAUCCAAUAUCUGCAGGUUUCUAACAGCAAGCCAGGACAAAAUACUCUUCAAGGACGUGAACAGGAAGCUGAGUGAUGUCUGGAAGGAGCUCUCGCUGUUACUUCAGGUUGAGCAACGCAUGCCUGUUUCACCCAUAAGCCAAGGAGCGUCCUGGGCACAGGAAGAUCAGCAGGAUGCAGACGAAGACAGGCGAGCUUUCCAGAUGCUAAGAAGAGAUAAUGAAAAAAUAGAAGCUUCACUGAGACGAUUAGAAAUCAACAUGAAAGAAAUCAAGGAAACUUUGAGGCAGUAUUUACCACCAAAAUGCAUGCAGGAGAUCCCGCAAGAGCAAAUCAAGGAGAUCAAGAAGGAGCAGCUUUCAGGAUCCCCGUGGAUUCUGCUAAGGGAAAAUGAAGUCAGCACACUUUAUAAAGGAGAAUACCACAGAGCUCCAGUGGCCAUAAAAGUAUUCAAAAAACUCCAGGCUGGCAGCAUUGCAAUAGUGAGGCAGACUUUCAAUAAGGAGAUCAAAACCAUGAAGAAAUUCGAAUCUCCCAACAPCCUGCGUAUAUUUGGGAUUUGCAUUGAUGAAACAGUGACUCCGCCUCAAUUCUCCAUUGUCAUGGAGUACUGUGAACUCGGGACCCUGAGGGAGCUGUUGGAUAGGGAAAAAGACCUCACACUUGGCAAGCGCAUGGUCCUAGUCCUGGGGGCAGCCCGAGGCCUAUACCGGCUACACCAUUCAGAAGCACCUGAACUCCACGGAAAAAUCAGAAGCUCAAACUUCCUGGUAACUCAAGGCUACCAAGUGAAGCUUGCAGGAUPUGAGUUGAGGAAAACACAGACUUCCAUGAGUUUGGGAACUACGAGAGAAAAGACAGACAGAGUCAAAUCUACAGCAUAUCUCUCACCUCAGGAACUGGAAGAUGUAUUUUAUCAAUAUGAUGUAAAGUCUGAAAUAUACAGCUUUGGAAUCGUCCUCUGGGAAAUCGCCACUGGAGAUAUCCCGUUUCAAGGCUGUAAUUCUGAGAAGAUCCGCAAGCUGGUGGCUGUGAAGCGGCAGCAGGAGCCACUGGGUGAAGACUGCCCUUCAGAGCUGCGGGAGAUCAUUGAUGAGUGCCGGGCCCAUGAUCCCUCUGUGCGGCCCUCUGUGGAUGAAAUCUUAAAGAAACUCUCCACCUUUUCUAAGUAGUGUAUCAAAAUCUAAACCAAGGAGUCUCUGGACAAGAAGCUGGGAGAGGCACAAACUGGЖCAUCUCUCUCUCUCAUAUCCUUCGGCAUUGGGUUAUCUAUGGGUGCAAGGAGUGGGCACGCUUCUCUGUUACAAAUAGAAAACGAUUCCAGUCAUACAGGACACAPCCCACUCCAAAUGAUAUUUCCAAAAACAUACCUCUGACAGUAЖCUUUGAUAGAUGGUUUGUCAAAUGUAUCUUUCUGGGUAUCCACACCUCUUGGCAAUGAAAUUUGCAGCUCCUCCCUUCCAUAAAUGAAGUCUCUUUCCCCACCAUUUGAAUCUGGGCUGGCACUGUGACUUGAUUUGAUCAAUAGAAUGUGGAAGAAGUGЖCUGUAUGCCAGUUCCAAGCCUAGGUUUCAAGAGGCCUUAUAAAUGUCUGUUGGAACCUUACCCAGCCAUGAACAUGUUGAGUGAGCAUGCUGGAGAAUGAGAGACCACAUGAAGCAGAAACAUGCUUUCCUAGCUGAAGUCAUACUAGCCCAACCAACAUGGCAGCUAЖCACAUGAAUGAGGCCAAUCAAGACCAGAAGAACCACUCAAGCAGAUCCCAGCCCAAAUUGCCCAUUCACACAAUCAGGAGCUAAAUAAAUUACUGUUGUCUUAACACUAA
Sequence (SHORT NAMES ENCODING)	GUGAGCCUGGUGGUUGGCAGCUGGAGCCACGUCGGAGGGGGAAGUGUCGCAGCAUUCUCUGCAGGCAUCACAGACCUGAGGCAGUGGCCUCCGGAGGGCACUGGACAGAAACAGCCAUCCAAGUGGCUGAGUGGAGGGACCCUGCUCAAGUGCAGCUGCAGUGGCCGGGGUUUCCCUCAGGUAGGGAUCGGGGCGCCUUGUCGCCGCCAGCCACGUGUGGCGUCCGGUACAGUCAGCAGAGUGCAGGGUGCGGGCACCAGGAAAGGGGGCGCAGGGGAACUCCCGCGGGCCUCGCGUUUGCAAACUUCUCGCCUGGGCAGGAGGCGGUCGUGGGAAAGAAGGUGGAAGAGCGAGCUUUUUGGAACUGUGCACGGGACAGAUUGGACGCACACCCCUCGGGAGGCGCGAAGGCAUGGAAAAUUUGAAGCAUAUUAUCACCCUUGGCCAGGUCAUCCACAAACGGUGUGAAGAGAUGAAAUACUGCAAGAAACAGUGCCGGCGCCUGGGCCACCGCGUCCUCGGCCUGAUCAAGCCUCUGGAGAUGCUCCAGGACCAAGGAAAGAGGAGCGUGCCCUCUGAGAAGUUAACCACAGCCAUGAACCGCUUCAAGGCUGCCCUGGAGGAGGCUAAUGGGGAGAUAGAAAAGUUCAGCAAUAGAUCCAAUAUCUGCAGGUUUCUAACAGCAAGCCAGGACAAAAUACUCUUCAAGGACGUGAACAGGAAGCUGAGUGAUGUCUGGAAGGAGCUCUCGCUGUUACUUCAGGUUGAGCAACGCAUGCCUGUUUCACCCAUAAGCCAAGGAGCGUCCUGGGCACAGGAAGAUCAGCAGGAUGCAGACGAAGACAGGCGAGCUUUCCAGAUGCUAAGAAGAGAUAAUGAAAAAAUAGAAGCUUCACUGAGACGAUUAGAAAUCAACAUGAAAGAAAUCAAGGAAACUUUGAGGCAGUAUUUACCACCAAAAUGCAUGCAGGAGAUCCCGCAAGAGCAAAUCAAGGAGAUCAAGAAGGAGCAGCUUUCAGGAUCCCCGUGGAUUCUGCUAAGGGAAAAUGAAGUCAGCACACUUUAUAAAGGAGAAUACCACAGAGCUCCAGUGGCCAUAAAAGUAUUCAAAAAACUCCAGGCUGGCAGCAUUGCAAUAGUGAGGCAGACUUUCAAUAAGGAGAUCAAAACCAUGAAGAAAUUCGAAUCUCCCAACAYCCUGCGUAUAUUUGGGAUUUGCAUUGAUGAAACAGUGACUCCGCCUCAAUUCUCCAUUGUCAUGGAGUACUGUGAACUCGGGACCCUGAGGGAGCUGUUGGAUAGGGAAAAAGACCUCACACUUGGCAAGCGCAUGGUCCUAGUCCUGGGGGCAGCCCGAGGCCUAUACCGGCUACACCAUUCAGAAGCACCUGAACUCCACGGAAAAAUCAGAAGCUCAAACUUCCUGGUAACUCAAGGCUACCAAGUGAAGCUUGCAGGAUYUGAGUUGAGGAAAACACAGACUUCCAUGAGUUUGGGAACUACGAGAGAAAAGACAGACAGAGUCAAAUCUACAGCAUAUCUCUCACCUCAGGAACUGGAAGAUGUAUUUUAUCAAUAUGAUGUAAAGUCUGAAAUAUACAGCUUUGGAAUCGUCCUCUGGGAAAUCGCCACUGGAGAUAUCCCGUUUCAAGGCUGUAAUUCUGAGAAGAUCCGCAAGCUGGUGGCUGUGAAGCGGCAGCAGGAGCCACUGGGUGAAGACUGCCCUUCAGAGCUGCGGGAGAUCAUUGAUGAGUGCCGGGCCCAUGAUCCCUCUGUGCGGCCCUCUGUGGAUGAAAUCUUAAAGAAACUCUCCACCUUUUCUAAGUAGUGUAUCAAAAUCUAAACCAAGGAGUCUCUGGACAAGAAGCUGGGAGAGGCACAAACUGGm6ACAUCUCUCUCUCUCAUAUCCUUCGGCAUUGGGUUAUCUAUGGGUGCAAGGAGUGGGCACGCUUCUCUGUUACAAAUAGAAAACGAUUCCAGUCAUACAGGACACAYCCCACUCCAAAUGAUAUUUCCAAAAACAUACCUCUGACAGUAm6ACUUUGAUAGAUGGUUUGUCAAAUGUAUCUUUCUGGGUAUCCACACCUCUUGGCAAUGAAAUUUGCAGCUCCUCCCUUCCAUAAAUGAAGUCUCUUUCCCCACCAUUUGAAUCUGGGCUGGCACUGUGACUUGAUUUGAUCAAUAGAAUGUGGAAGAAGUGm6ACUGUAUGCCAGUUCCAAGCCUAGGUUUCAAGAGGCCUUAUAAAUGUCUGUUGGAACCUUACCCAGCCAUGAACAUGUUGAGUGAGCAUGCUGGAGAAUGAGAGACCACAUGAAGCAGAAACAUGCUUUCCUAGCUGAAGUCAUACUAGCCCAACCAACAUGGCAGCUAm6ACACAUGAAUGAGGCCAAUCAAGACCAGAAGAACCACUCAAGCAGAUCCCAGCCCAAAUUGCCCAUUCACACAAUCAGGAGCUAAAUAAAUUACUGUUGUCUUAACACUAA
Sequence (MODOMICS CODE ENCODING)	GUGAGCCUGGUGGUUGGCAGCUGGAGCCACGUCGGAGGGGGAAGUGUCGCAGCAUUCUCUGCAGGCAUCACAGACCUGAGGCAGUGGCCUCCGGAGGGCACUGGACAGAAACAGCCAUCCAAGUGGCUGAGUGGAGGGACCCUGCUCAAGUGCAGCUGCAGUGGCCGGGGUUUCCCUCAGGUAGGGAUCGGGGCGCCUUGUCGCCGCCAGCCACGUGUGGCGUCCGGUACAGUCAGCAGAGUGCAGGGUGCGGGCACCAGGAAAGGGGGCGCAGGGGAACUCCCGCGGGCCUCGCGUUUGCAAACUUCUCGCCUGGGCAGGAGGCGGUCGUGGGAAAGAAGGUGGAAGAGCGAGCUUUUUGGAACUGUGCACGGGACAGAUUGGACGCACACCCCUCGGGAGGCGCGAAGGCAUGGAAAAUUUGAAGCAUAUUAUCACCCUUGGCCAGGUCAUCCACAAACGGUGUGAAGAGAUGAAAUACUGCAAGAAACAGUGCCGGCGCCUGGGCCACCGCGUCCUCGGCCUGAUCAAGCCUCUGGAGAUGCUCCAGGACCAAGGAAAGAGGAGCGUGCCCUCUGAGAAGUUAACCACAGCCAUGAACCGCUUCAAGGCUGCCCUGGAGGAGGCUAAUGGGGAGAUAGAAAAGUUCAGCAAUAGAUCCAAUAUCUGCAGGUUUCUAACAGCAAGCCAGGACAAAAUACUCUUCAAGGACGUGAACAGGAAGCUGAGUGAUGUCUGGAAGGAGCUCUCGCUGUUACUUCAGGUUGAGCAACGCAUGCCUGUUUCACCCAUAAGCCAAGGAGCGUCCUGGGCACAGGAAGAUCAGCAGGAUGCAGACGAAGACAGGCGAGCUUUCCAGAUGCUAAGAAGAGAUAAUGAAAAAAUAGAAGCUUCACUGAGACGAUUAGAAAUCAACAUGAAAGAAAUCAAGGAAACUUUGAGGCAGUAUUUACCACCAAAAUGCAUGCAGGAGAUCCCGCAAGAGCAAAUCAAGGAGAUCAAGAAGGAGCAGCUUUCAGGAUCCCCGUGGAUUCUGCUAAGGGAAAAUGAAGUCAGCACACUUUAUAAAGGAGAAUACCACAGAGCUCCAGUGGCCAUAAAAGUAUUCAAAAAACUCCAGGCUGGCAGCAUUGCAAUAGUGAGGCAGACUUUCAAUAAGGAGAUCAAAACCAUGAAGAAAUUCGAAUCUCCCAACA2000000009UCCUGCGUAUAUUUGGGAUUUGCAUUGAUGAAACAGUGACUCCGCCUCAAUUCUCCAUUGUCAUGGAGUACUGUGAACUCGGGACCCUGAGGGAGCUGUUGGAUAGGGAAAAAGACCUCACACUUGGCAAGCGCAUGGUCCUAGUCCUGGGGGCAGCCCGAGGCCUAUACCGGCUACACCAUUCAGAAGCACCUGAACUCCACGGAAAAAUCAGAAGCUCAAACUUCCUGGUAACUCAAGGCUACCAAGUGAAGCUUGCAGGAU2000000009UUGAGUUGAGGAAAACACAGACUUCCAUGAGUUUGGGAACUACGAGAGAAAAGACAGACAGAGUCAAAUCUACAGCAUAUCUCUCACCUCAGGAACUGGAAGAUGUAUUUUAUCAAUAUGAUGUAAAGUCUGAAAUAUACAGCUUUGGAAUCGUCCUCUGGGAAAUCGCCACUGGAGAUAUCCCGUUUCAAGGCUGUAAUUCUGAGAAGAUCCGCAAGCUGGUGGCUGUGAAGCGGCAGCAGGAGCCACUGGGUGAAGACUGCCCUUCAGAGCUGCGGGAGAUCAUUGAUGAGUGCCGGGCCCAUGAUCCCUCUGUGCGGCCCUCUGUGGAUGAAAUCUUAAAGAAACUCUCCACCUUUUCUAAGUAGUGUAUCAAAAUCUAAACCAAGGAGUCUCUGGACAAGAAGCUGGGAGAGGCACAAACUGG2000000006ACAUCUCUCUCUCUCAUAUCCUUCGGCAUUGGGUUAUCUAUGGGUGCAAGGAGUGGGCACGCUUCUCUGUUACAAAUAGAAAACGAUUCCAGUCAUACAGGACACA2000000009UCCCACUCCAAAUGAUAUUUCCAAAAACAUACCUCUGACAGUA2000000006ACUUUGAUAGAUGGUUUGUCAAAUGUAUCUUUCUGGGUAUCCACACCUCUUGGCAAUGAAAUUUGCAGCUCCUCCCUUCCAUAAAUGAAGUCUCUUUCCCCACCAUUUGAAUCUGGGCUGGCACUGUGACUUGAUUUGAUCAAUAGAAUGUGGAAGAAGUG2000000006ACUGUAUGCCAGUUCCAAGCCUAGGUUUCAAGAGGCCUUAUAAAUGUCUGUUGGAACCUUACCCAGCCAUGAACAUGUUGAGUGAGCAUGCUGGAGAAUGAGAGACCACAUGAAGCAGAAACAUGCUUUCCUAGCUGAAGUCAUACUAGCCCAACCAACAUGGCAGCUA2000000006ACACAUGAAUGAGGCCAAUCAAGACCAGAAGAACCACUCAAGCAGAUCCCAGCCCAAAUUGCCCAUUCACACAAUCAGGAGCUAAAUAAAUUACUGUUGUCUUAACACUAA

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	1197	1461	1888	1994	2037	2198	2367
Modification Positions	Y	Y	m6A	Y	m6A	m6A	m6A
Genomic Coordinates	16:74685521:-	16:74675754:-	16:74672444:-	16:74672338:-	16:74672295:-	16:74672134:-	16:74671965:-
Level of Experimental Evidence	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	bXBqJigD9oV3 dknfVe6BK8aP	bXBqJigD9oV3 dknfVe6BK8aP	3TeAZFYFxgvp NjZ8bGGJsNSR Q36pf44ZRvxu UN3tNpbCPHYf VL7zkHvkfkoB WdHxkJGRmFxn KTLz8piFYdwC WiQcrNTGZHPT bXBqJigD9oV3 dknfVe6BK8aP	bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr	jNkxUQNx8GRd WdHxkJGRmFxn bXBqJigD9oV3 dknfVe6BK8aP	3TeAZFYFxgvp 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB WdHxkJGRmFxn KENzb7mwdBd9 Lny8GcCeVGc9 UKen6WEino9G bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr	bXBqJigD9oV3 dknfVe6BK8aP