General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000700391
Gene ID:	ENSG00000080815
Gene Name:	PSEN1
Sequence (UNICHARACTER ENCODING)	GGAAUCUUGCUGGCCUGAACAGUUUUCCUUCUGGUUCCUUUUCAGGGACUAAAAAUGAUGAAGAGUUUUGUGAUAGCAGCAACAAUGGUGUGGUUGGUGAAUAUGGCAGAAGGAGACCCGGAAGCUCAAAGGAGAGUAUCCAAAAAUUCCAAGUAUAAUGCAGAAAGCACAGAAAGGGAGUCACAAGACACUGUUGCAGAGAAUGAUGAUGGCGGGUUCAGUGAGGAAUGGGAAGCCCAGAGGGACAGUCAUCUAGGGCCUCAUCGCUCUACACCUGAGUCACGAGCUGCUGUCCAGGAACUUUCCAGCAGUAUCCUCGCUGGUGAAGACCCAGAGGAAAGGGGAGUAAAACUUGGAUUGGGAGAUUUCAUUUUCUACAGUGUUCUGGUUGGUAAAGCCUCAGCAACAGCCAGUGGAGACUGGAACACAACCAUAGCCUGUUUCGUAGCCAUAUUAAUUGGUUUGUGCCUUACAUUAUUACUCCUUGCCAUUUUCAAGAAAGCAUUGCCAGCUCUUCCAAUCUCCAUCACCUUUGGGCUUGUUUUCUACUUUGCCACAGAUUAUCUUGUACAGCCUUUUAUGGЖCCAAUUAGCAUUCCAUCAAUUUUAUAUCUAGCAUAUUUGCGGUUAGAAUCCCAUGGAUGUUUCUUCUUUGЖCUAUAACAAAAUCUGGGGAGGACAAAGGUGAUUUUCCUGUGUCCACAUCUAACAAAGUCAAGAUUCCCGGCUGGЖCUUUUGCAGCUUCCUUCCAAGUCUUCCUGACCACCUUGCACUAUUGGЖCUUUGGAAGGAGGUGCCUAUAGAAAACGAUUUUGAACAUACUUCAUCGCAGUGGЖCUGUGUCCCUCGGUGCAGAAACUACCAGAUUUGAGGGACGAGGUCAAGGAGAUAUGAUAGGCCCGGAAGUUGCUGUGCCCCAUCAGCAGCUUGACGCGUGGUCACAGGЖCGAUUUCACUGACACUGCGAЖCUCUCAGGЖCUACCGUUACCAAGAGGUUAGGUGAAGUGGUUUAAACCAAACGGAЖCUCUUCAUCUUAAACUACACGUUGAAAAUCAACCCAAUAAUUCUGUAUUAACUGAAUUCUGAЖCUUUUCAGGAGGUACUGUGAGGAAGAGCAGGCACCAGCAGCAGAAUGGGGAAUGGAGAGGUGGGCAGGGGUUCCAGCUUCCCUUUGAUUUUUUGCUGCAGACUCAPCCUUUUUAAAUGAGACUUGUUUUCCCCUCUCUUUGAGUCAAGUCAAAUAUGUAGAUUGCCUUUGGCAAUUCUUCUUCUCAAGCACUGACACUCAUUACCGUCUGUGAUUGCCAUUUCUUCCCAAGGCCAGUCUGAACCUGAGGUUGCUPUAUCCUAAAAGUUUUAACCUCAGGUUCCAAAUUCAGUAAAUUUUGGAAACAGUACAGCUAUUUCUCAUCAAUUCUCUAUCAUGUUGAAGUCAAAUUUGGAUUUUCCACCAAAUUCUGAAUUUGUAGЖCAUACUUGUACGCUCACUUGCCCCAGAUGCCUCCUCUGUCCUCAUUCUUCUCUCCCACACAAGCAGUCUUUUUCUACAGCCAGUAAGGCAGCUCUGUCGUGGUAGCAGAUGGUCCCAUUAUUCUAGGGUCUUACUCUUUGUAUGAUGAAAAGAAUGUGUUAUGAAUCGGUGCUGUCAGCCCUGCUGUCAGACCUUCUUCCACAGCAAAUGAGAUGUAUGCCCAAAGACGGUAGAAUUAAAGAAGAGUAAAAUGGCUGUUGAAGCA
Sequence (SHORT NAMES ENCODING)	GGAAUCUUGCUGGCCUGAACAGUUUUCCUUCUGGUUCCUUUUCAGGGACUAAAAAUGAUGAAGAGUUUUGUGAUAGCAGCAACAAUGGUGUGGUUGGUGAAUAUGGCAGAAGGAGACCCGGAAGCUCAAAGGAGAGUAUCCAAAAAUUCCAAGUAUAAUGCAGAAAGCACAGAAAGGGAGUCACAAGACACUGUUGCAGAGAAUGAUGAUGGCGGGUUCAGUGAGGAAUGGGAAGCCCAGAGGGACAGUCAUCUAGGGCCUCAUCGCUCUACACCUGAGUCACGAGCUGCUGUCCAGGAACUUUCCAGCAGUAUCCUCGCUGGUGAAGACCCAGAGGAAAGGGGAGUAAAACUUGGAUUGGGAGAUUUCAUUUUCUACAGUGUUCUGGUUGGUAAAGCCUCAGCAACAGCCAGUGGAGACUGGAACACAACCAUAGCCUGUUUCGUAGCCAUAUUAAUUGGUUUGUGCCUUACAUUAUUACUCCUUGCCAUUUUCAAGAAAGCAUUGCCAGCUCUUCCAAUCUCCAUCACCUUUGGGCUUGUUUUCUACUUUGCCACAGAUUAUCUUGUACAGCCUUUUAUGGm6ACCAAUUAGCAUUCCAUCAAUUUUAUAUCUAGCAUAUUUGCGGUUAGAAUCCCAUGGAUGUUUCUUCUUUGm6ACUAUAACAAAAUCUGGGGAGGACAAAGGUGAUUUUCCUGUGUCCACAUCUAACAAAGUCAAGAUUCCCGGCUGGm6ACUUUUGCAGCUUCCUUCCAAGUCUUCCUGACCACCUUGCACUAUUGGm6ACUUUGGAAGGAGGUGCCUAUAGAAAACGAUUUUGAACAUACUUCAUCGCAGUGGm6ACUGUGUCCCUCGGUGCAGAAACUACCAGAUUUGAGGGACGAGGUCAAGGAGAUAUGAUAGGCCCGGAAGUUGCUGUGCCCCAUCAGCAGCUUGACGCGUGGUCACAGGm6ACGAUUUCACUGACACUGCGAm6ACUCUCAGGm6ACUACCGUUACCAAGAGGUUAGGUGAAGUGGUUUAAACCAAACGGAm6ACUCUUCAUCUUAAACUACACGUUGAAAAUCAACCCAAUAAUUCUGUAUUAACUGAAUUCUGAm6ACUUUUCAGGAGGUACUGUGAGGAAGAGCAGGCACCAGCAGCAGAAUGGGGAAUGGAGAGGUGGGCAGGGGUUCCAGCUUCCCUUUGAUUUUUUGCUGCAGACUCAYCCUUUUUAAAUGAGACUUGUUUUCCCCUCUCUUUGAGUCAAGUCAAAUAUGUAGAUUGCCUUUGGCAAUUCUUCUUCUCAAGCACUGACACUCAUUACCGUCUGUGAUUGCCAUUUCUUCCCAAGGCCAGUCUGAACCUGAGGUUGCUYUAUCCUAAAAGUUUUAACCUCAGGUUCCAAAUUCAGUAAAUUUUGGAAACAGUACAGCUAUUUCUCAUCAAUUCUCUAUCAUGUUGAAGUCAAAUUUGGAUUUUCCACCAAAUUCUGAAUUUGUAGm6ACAUACUUGUACGCUCACUUGCCCCAGAUGCCUCCUCUGUCCUCAUUCUUCUCUCCCACACAAGCAGUCUUUUUCUACAGCCAGUAAGGCAGCUCUGUCGUGGUAGCAGAUGGUCCCAUUAUUCUAGGGUCUUACUCUUUGUAUGAUGAAAAGAAUGUGUUAUGAAUCGGUGCUGUCAGCCCUGCUGUCAGACCUUCUUCCACAGCAAAUGAGAUGUAUGCCCAAAGACGGUAGAAUUAAAGAAGAGUAAAAUGGCUGUUGAAGCA
Sequence (MODOMICS CODE ENCODING)	GGAAUCUUGCUGGCCUGAACAGUUUUCCUUCUGGUUCCUUUUCAGGGACUAAAAAUGAUGAAGAGUUUUGUGAUAGCAGCAACAAUGGUGUGGUUGGUGAAUAUGGCAGAAGGAGACCCGGAAGCUCAAAGGAGAGUAUCCAAAAAUUCCAAGUAUAAUGCAGAAAGCACAGAAAGGGAGUCACAAGACACUGUUGCAGAGAAUGAUGAUGGCGGGUUCAGUGAGGAAUGGGAAGCCCAGAGGGACAGUCAUCUAGGGCCUCAUCGCUCUACACCUGAGUCACGAGCUGCUGUCCAGGAACUUUCCAGCAGUAUCCUCGCUGGUGAAGACCCAGAGGAAAGGGGAGUAAAACUUGGAUUGGGAGAUUUCAUUUUCUACAGUGUUCUGGUUGGUAAAGCCUCAGCAACAGCCAGUGGAGACUGGAACACAACCAUAGCCUGUUUCGUAGCCAUAUUAAUUGGUUUGUGCCUUACAUUAUUACUCCUUGCCAUUUUCAAGAAAGCAUUGCCAGCUCUUCCAAUCUCCAUCACCUUUGGGCUUGUUUUCUACUUUGCCACAGAUUAUCUUGUACAGCCUUUUAUGG2000000006ACCAAUUAGCAUUCCAUCAAUUUUAUAUCUAGCAUAUUUGCGGUUAGAAUCCCAUGGAUGUUUCUUCUUUG2000000006ACUAUAACAAAAUCUGGGGAGGACAAAGGUGAUUUUCCUGUGUCCACAUCUAACAAAGUCAAGAUUCCCGGCUGG2000000006ACUUUUGCAGCUUCCUUCCAAGUCUUCCUGACCACCUUGCACUAUUGG2000000006ACUUUGGAAGGAGGUGCCUAUAGAAAACGAUUUUGAACAUACUUCAUCGCAGUGG2000000006ACUGUGUCCCUCGGUGCAGAAACUACCAGAUUUGAGGGACGAGGUCAAGGAGAUAUGAUAGGCCCGGAAGUUGCUGUGCCCCAUCAGCAGCUUGACGCGUGGUCACAGG2000000006ACGAUUUCACUGACACUGCGA2000000006ACUCUCAGG2000000006ACUACCGUUACCAAGAGGUUAGGUGAAGUGGUUUAAACCAAACGGA2000000006ACUCUUCAUCUUAAACUACACGUUGAAAAUCAACCCAAUAAUUCUGUAUUAACUGAAUUCUGA2000000006ACUUUUCAGGAGGUACUGUGAGGAAGAGCAGGCACCAGCAGCAGAAUGGGGAAUGGAGAGGUGGGCAGGGGUUCCAGCUUCCCUUUGAUUUUUUGCUGCAGACUCA2000000009UCCUUUUUAAAUGAGACUUGUUUUCCCCUCUCUUUGAGUCAAGUCAAAUAUGUAGAUUGCCUUUGGCAAUUCUUCUUCUCAAGCACUGACACUCAUUACCGUCUGUGAUUGCCAUUUCUUCCCAAGGCCAGUCUGAACCUGAGGUUGCU2000000009UUAUCCUAAAAGUUUUAACCUCAGGUUCCAAAUUCAGUAAAUUUUGGAAACAGUACAGCUAUUUCUCAUCAAUUCUCUAUCAUGUUGAAGUCAAAUUUGGAUUUUCCACCAAAUUCUGAAUUUGUAG2000000006ACAUACUUGUACGCUCACUUGCCCCAGAUGCCUCCUCUGUCCUCAUUCUUCUCUCCCACACAAGCAGUCUUUUUCUACAGCCAGUAAGGCAGCUCUGUCGUGGUAGCAGAUGGUCCCAUUAUUCUAGGGUCUUACUCUUUGUAUGAUGAAAAGAAUGUGUUAUGAAUCGGUGCUGUCAGCCCUGCUGUCAGACCUUCUUCCACAGCAAAUGAGAUGUAUGCCCAAAGACGGUAGAAUUAAAGAAGAGUAAAAUGGCUGUUGAAGCA

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	584	655	730	778	833	942	963	972	1018	1081	1187	1336	1463
Modification Positions	m6A	m6A	m6A	m6A	m6A	m6A	m6A	m6A	m6A	m6A	Y	Y	m6A
Genomic Coordinates	14:73219258:+	14:73219329:+	14:73219404:+	14:73219452:+	14:73219507:+	14:73219616:+	14:73219637:+	14:73219646:+	14:73219692:+	14:73219755:+	14:73219861:+	14:73220010:+	14:73220137:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	msuJfBpJvM5H VL7zkHvkfkoB VyCX26p5UBRL aJksAshEgQ8U D6ncpa2PPWj3 8cMbzB4aD5Se KTLz8piFYdwC WiQcrNTGZHPT BsCW7emuRX7M KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 LZJKems7W2wi PF5iqBNSbHaa UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 Yfn77uLS5tv8	4HMi5ykupT9V 5aTkEfEpX8Xm msuJfBpJvM5H VyCX26p5UBRL 93arJtwJmuS9 ArijeGVTwYBw KTLz8piFYdwC WiQcrNTGZHPT BsCW7emuRX7M KENzb7mwdBd9 Lny8GcCeVGc9 LZJKems7W2wi UKen6WEino9G BtsJQJ3DteUq bXBqJigD9oV3 S9vNeQQYrhac Yfn77uLS5tv8	3TeAZFYFxgvp 4HMi5ykupT9V 5aTkEfEpX8Xm 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U 8cMbzB4aD5Se ArijeGVTwYBw KTLz8piFYdwC nfCHyrYzE6fB WiQcrNTGZHPT KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 PF5iqBNSbHaa UKen6WEino9G BtsJQJ3DteUq bXBqJigD9oV3 f6YSioLdAWpr S9vNeQQYrhac Yfn77uLS5tv8	3TeAZFYFxgvp 4HMi5ykupT9V 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U D6ncpa2PPWj3 8cMbzB4aD5Se ArijeGVTwYBw KTLz8piFYdwC nfCHyrYzE6fB WiQcrNTGZHPT BsCW7emuRX7M KENzb7mwdBd9 Lny8GcCeVGc9 LZJKems7W2wi PF5iqBNSbHaa UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 iezFbUdmY3A6 Yfn77uLS5tv8	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U D6ncpa2PPWj3 8cMbzB4aD5Se ArijeGVTwYBw KTLz8piFYdwC nfCHyrYzE6fB WiQcrNTGZHPT BsCW7emuRX7M KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 LZJKems7W2wi UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 Yfn77uLS5tv8	3TeAZFYFxgvp 5aTkEfEpX8Xm 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U Lny8GcCeVGc9	3TeAZFYFxgvp 5aTkEfEpX8Xm 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BsCW7emuRX7M Lny8GcCeVGc9 LZJKems7W2wi UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	3TeAZFYFxgvp 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn 93arJtwJmuS9 ArijeGVTwYBw BkoLW2CBToyL nfCHyrYzE6fB BsCW7emuRX7M KENzb7mwdBd9 Lny8GcCeVGc9 XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	jNkxUQNx8GRd msuJfBpJvM5H VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BsCW7emuRX7M KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 LZJKems7W2wi PF5iqBNSbHaa UKen6WEino9G XUkp6ghERQML BtsJQJ3DteUq bXBqJigD9oV3 f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	4HMi5ykupT9V 5aTkEfEpX8Xm msuJfBpJvM5H VyCX26p5UBRL KjeH7Nsffuas Lny8GcCeVGc9 PF5iqBNSbHaa UKen6WEino9G BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	ArijeGVTwYBw BkoLW2CBToyL KTLz8piFYdwC BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8