General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000397440
Gene ID:	ENSG00000100462
Gene Name:	PRMT5
Sequence (UNICHARACTER ENCODING)	GGCGAUGGCGGUCGGGGGUGCUGGUGGGAGCCGCGUGUCCAGCGGGAGGGACCUGAAUUGCGUCCCCGAAAUAGCUGACACACUAGGGGCUGUGGCCAAGCAGGGGUGAGGGCCGGACCUCCACGAGCGGAAUGCGGGGUCCGAACUCGGGGACGGAGAAGGGCAGACUAGUCAUCCCGGAGAAGCAGGGGUUUGAUUUCCUCUGCAUGCCUGUCUUCCAPCCGCGUUUCAAGAGGGAGUUCAUUCAGGAACCUGCUAAGAAUCGGCCCGGUCCCCAGACACGAUCAGACCUACUGCUGUCAGGAAGGGACUGGAAUACGCUAAUUGUGGGAAAGCUUUCUCCAUGGAUUCGUCCAGACUCAAAAGUGGAGAAGAUUCGCAGGAACUCCGAGGCGUUGGAGGUGCAGUUCAUCAUCACAGGCACCAACCACCACUCAGAGAAGGAGUUCUGCUCCUACCUCCAAUACCUGGAAUACUUAAGCCAGAACCGUCCPCCACCUAAUGCCUAUGAACUCUUUGCCAAGGGCUAUGAAGACUAUCUGCAGUCCCCGCUUCAGCCACUGAUGGACAAUCUGGAAUCUCAGACAUAUGAAGUGUUUGAAAAGGACCCCAUCAAAUACUCUCAGUACCAGCAGGCCAUCUAUAAAUGUCUGCUAGЖCCGAGUACCAGAAGAGGAGAAGGAUACCAAUGUCCAGGUACUGAUGGUGCUGGGAGCAGGACGGGGACCCCUGGUGAACGCUUCCCUGCGGGCAGCCAAGCAGGCCGACCGGCGGAUAAAGCUGUAUGCUGUGGAGAAAAACCCЖAAUGCCGUGGUGACGCUAGAGAACUGGCAGUUUGAAGAAUGGGGAAGCCAAGUGACCGUAGUCUCAUCAGACAUGAGGGAAUGGGUGGCUCCAGAGAAAGCAGACAUCAUUGUCAGUGAGCUUCUGGGCUCAUUUGCUGACAAUGAAUUGUCGCCUGAGUGCCUGGAUGGAGCCCAGCACUUCCUAAAAGAUGAUGGUGUGAGCAUCCCCGGGGAGUACACUUCCUUUCUGGCUCCCAUCUCUUCCUCCAAGCUGUACAAUGAGGUCCGAGCCUGUAGGGAGAAGGACCGUGACCCUGAGGCCCAGUUUGAGAUGCCUUAUGUGGUACGGCUGCACAACUUCCACCAGCUCUCUGCACCCCAGCCCUGUUUCACCUUCAGCCAPCCCAACAGAGAUCCUAUGAUUGACAACAACCGCUAUUGCACCUUGGAAUUUCCUGUGGAGGUGAACACAGUACUACЖUGGCUUUGCCGGCUACUUUGAGACUGUGCUPUAUCAGGACAUCACUCUGAGUAUCCGUCCAGAGACUCACUCUCCUGGGAUGUUCUCAUGGUUUCCCAPCCUCUUCCCUAUUAAGCAGCCCAPAACGGUACGUGAAGGCCAAACCAUCUGUGUGCGUUUCUGGCGAUGCAGCAAUUCCAAGAAGGUGUGGUAUGAGUGGGCUGUGACAGCACCAGUCUGUUCUGCUAUUCAUAACCCCACAGGCCGCUCAUAUACCAUUGGCCUCUAGCCCUGCGUGCCAAGUGUCCAGAGCCUUGGAAGCAGCUUCAGGUUCUGCUCCUGUAGUACAGAAGGUGCAGUACAUCUAUGGGCUGUGAUUCCCCUUGCCCAUCAGAGAGGAGCAUUUCAAUCUGCUUUCCUGCCUUACAUCAAGGUGGGCAAGGGAUUAUAAUUAAUUGCAGGGCUCAAGCCACCAAUCUAUGAAGЖCCUCAGGCCAGGGGGUGAGGAAUUAGUGCUGGAUPUGAAGCUACGCACUCAGCCUCAAGAACUCCCUGGAAUAUCCCUGAGAACAUGGGGUUUGAACGGAUUUUCAGCCUUUUUCUGUUCUUGUUUUGAUGGUUUUGUGUAAGAGGAAAUACAAAUAAAGUUAUAGCCCUUUACUGCA
Sequence (SHORT NAMES ENCODING)	GGCGAUGGCGGUCGGGGGUGCUGGUGGGAGCCGCGUGUCCAGCGGGAGGGACCUGAAUUGCGUCCCCGAAAUAGCUGACACACUAGGGGCUGUGGCCAAGCAGGGGUGAGGGCCGGACCUCCACGAGCGGAAUGCGGGGUCCGAACUCGGGGACGGAGAAGGGCAGACUAGUCAUCCCGGAGAAGCAGGGGUUUGAUUUCCUCUGCAUGCCUGUCUUCCAYCCGCGUUUCAAGAGGGAGUUCAUUCAGGAACCUGCUAAGAAUCGGCCCGGUCCCCAGACACGAUCAGACCUACUGCUGUCAGGAAGGGACUGGAAUACGCUAAUUGUGGGAAAGCUUUCUCCAUGGAUUCGUCCAGACUCAAAAGUGGAGAAGAUUCGCAGGAACUCCGAGGCGUUGGAGGUGCAGUUCAUCAUCACAGGCACCAACCACCACUCAGAGAAGGAGUUCUGCUCCUACCUCCAAUACCUGGAAUACUUAAGCCAGAACCGUCCYCCACCUAAUGCCUAUGAACUCUUUGCCAAGGGCUAUGAAGACUAUCUGCAGUCCCCGCUUCAGCCACUGAUGGACAAUCUGGAAUCUCAGACAUAUGAAGUGUUUGAAAAGGACCCCAUCAAAUACUCUCAGUACCAGCAGGCCAUCUAUAAAUGUCUGCUAGm6ACCGAGUACCAGAAGAGGAGAAGGAUACCAAUGUCCAGGUACUGAUGGUGCUGGGAGCAGGACGGGGACCCCUGGUGAACGCUUCCCUGCGGGCAGCCAAGCAGGCCGACCGGCGGAUAAAGCUGUAUGCUGUGGAGAAAAACCCm6AAAUGCCGUGGUGACGCUAGAGAACUGGCAGUUUGAAGAAUGGGGAAGCCAAGUGACCGUAGUCUCAUCAGACAUGAGGGAAUGGGUGGCUCCAGAGAAAGCAGACAUCAUUGUCAGUGAGCUUCUGGGCUCAUUUGCUGACAAUGAAUUGUCGCCUGAGUGCCUGGAUGGAGCCCAGCACUUCCUAAAAGAUGAUGGUGUGAGCAUCCCCGGGGAGUACACUUCCUUUCUGGCUCCCAUCUCUUCCUCCAAGCUGUACAAUGAGGUCCGAGCCUGUAGGGAGAAGGACCGUGACCCUGAGGCCCAGUUUGAGAUGCCUUAUGUGGUACGGCUGCACAACUUCCACCAGCUCUCUGCACCCCAGCCCUGUUUCACCUUCAGCCAYCCCAACAGAGAUCCUAUGAUUGACAACAACCGCUAUUGCACCUUGGAAUUUCCUGUGGAGGUGAACACAGUACUACm6AUGGCUUUGCCGGCUACUUUGAGACUGUGCUYUAUCAGGACAUCACUCUGAGUAUCCGUCCAGAGACUCACUCUCCUGGGAUGUUCUCAUGGUUUCCCAYCCUCUUCCCUAUUAAGCAGCCCAYAACGGUACGUGAAGGCCAAACCAUCUGUGUGCGUUUCUGGCGAUGCAGCAAUUCCAAGAAGGUGUGGUAUGAGUGGGCUGUGACAGCACCAGUCUGUUCUGCUAUUCAUAACCCCACAGGCCGCUCAUAUACCAUUGGCCUCUAGCCCUGCGUGCCAAGUGUCCAGAGCCUUGGAAGCAGCUUCAGGUUCUGCUCCUGUAGUACAGAAGGUGCAGUACAUCUAUGGGCUGUGAUUCCCCUUGCCCAUCAGAGAGGAGCAUUUCAAUCUGCUUUCCUGCCUUACAUCAAGGUGGGCAAGGGAUUAUAAUUAAUUGCAGGGCUCAAGCCACCAAUCUAUGAAGm6ACCUCAGGCCAGGGGGUGAGGAAUUAGUGCUGGAUYUGAAGCUACGCACUCAGCCUCAAGAACUCCCUGGAAUAUCCCUGAGAACAUGGGGUUUGAACGGAUUUUCAGCCUUUUUCUGUUCUUGUUUUGAUGGUUUUGUGUAAGAGGAAAUACAAAUAAAGUUAUAGCCCUUUACUGCA
Sequence (MODOMICS CODE ENCODING)	GGCGAUGGCGGUCGGGGGUGCUGGUGGGAGCCGCGUGUCCAGCGGGAGGGACCUGAAUUGCGUCCCCGAAAUAGCUGACACACUAGGGGCUGUGGCCAAGCAGGGGUGAGGGCCGGACCUCCACGAGCGGAAUGCGGGGUCCGAACUCGGGGACGGAGAAGGGCAGACUAGUCAUCCCGGAGAAGCAGGGGUUUGAUUUCCUCUGCAUGCCUGUCUUCCA2000000009UCCGCGUUUCAAGAGGGAGUUCAUUCAGGAACCUGCUAAGAAUCGGCCCGGUCCCCAGACACGAUCAGACCUACUGCUGUCAGGAAGGGACUGGAAUACGCUAAUUGUGGGAAAGCUUUCUCCAUGGAUUCGUCCAGACUCAAAAGUGGAGAAGAUUCGCAGGAACUCCGAGGCGUUGGAGGUGCAGUUCAUCAUCACAGGCACCAACCACCACUCAGAGAAGGAGUUCUGCUCCUACCUCCAAUACCUGGAAUACUUAAGCCAGAACCGUCC2000000009UCCACCUAAUGCCUAUGAACUCUUUGCCAAGGGCUAUGAAGACUAUCUGCAGUCCCCGCUUCAGCCACUGAUGGACAAUCUGGAAUCUCAGACAUAUGAAGUGUUUGAAAAGGACCCCAUCAAAUACUCUCAGUACCAGCAGGCCAUCUAUAAAUGUCUGCUAG2000000006ACCGAGUACCAGAAGAGGAGAAGGAUACCAAUGUCCAGGUACUGAUGGUGCUGGGAGCAGGACGGGGACCCCUGGUGAACGCUUCCCUGCGGGCAGCCAAGCAGGCCGACCGGCGGAUAAAGCUGUAUGCUGUGGAGAAAAACCC2000000006AAAUGCCGUGGUGACGCUAGAGAACUGGCAGUUUGAAGAAUGGGGAAGCCAAGUGACCGUAGUCUCAUCAGACAUGAGGGAAUGGGUGGCUCCAGAGAAAGCAGACAUCAUUGUCAGUGAGCUUCUGGGCUCAUUUGCUGACAAUGAAUUGUCGCCUGAGUGCCUGGAUGGAGCCCAGCACUUCCUAAAAGAUGAUGGUGUGAGCAUCCCCGGGGAGUACACUUCCUUUCUGGCUCCCAUCUCUUCCUCCAAGCUGUACAAUGAGGUCCGAGCCUGUAGGGAGAAGGACCGUGACCCUGAGGCCCAGUUUGAGAUGCCUUAUGUGGUACGGCUGCACAACUUCCACCAGCUCUCUGCACCCCAGCCCUGUUUCACCUUCAGCCA2000000009UCCCAACAGAGAUCCUAUGAUUGACAACAACCGCUAUUGCACCUUGGAAUUUCCUGUGGAGGUGAACACAGUACUAC2000000006AUGGCUUUGCCGGCUACUUUGAGACUGUGCU2000000009UUAUCAGGACAUCACUCUGAGUAUCCGUCCAGAGACUCACUCUCCUGGGAUGUUCUCAUGGUUUCCCA2000000009UCCUCUUCCCUAUUAAGCAGCCCA2000000009UAACGGUACGUGAAGGCCAAACCAUCUGUGUGCGUUUCUGGCGAUGCAGCAAUUCCAAGAAGGUGUGGUAUGAGUGGGCUGUGACAGCACCAGUCUGUUCUGCUAUUCAUAACCCCACAGGCCGCUCAUAUACCAUUGGCCUCUAGCCCUGCGUGCCAAGUGUCCAGAGCCUUGGAAGCAGCUUCAGGUUCUGCUCCUGUAGUACAGAAGGUGCAGUACAUCUAUGGGCUGUGAUUCCCCUUGCCCAUCAGAGAGGAGCAUUUCAAUCUGCUUUCCUGCCUUACAUCAAGGUGGGCAAGGGAUUAUAAUUAAUUGCAGGGCUCAAGCCACCAAUCUAUGAAG2000000006ACCUCAGGCCAGGGGGUGAGGAAUUAGUGCUGGAU2000000009UUGAAGCUACGCACUCAGCCUCAAGAACUCCCUGGAAUAUCCCUGAGAACAUGGGGUUUGAACGGAUUUUCAGCCUUUUUCUGUUCUUGUUUUGAUGGUUUUGUGUAAGAGGAAAUACAAAUAAAGUUAUAGCCCUUUACUGCA

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	221	494	658	803	1187	1264	1295	1363	1387	1729	1764
Modification Positions	Y	Y	m6A	m6A	Y	m6A	Y	Y	Y	m6A	Y
Genomic Coordinates	14:22928585:-	14:22924942:-	14:22924515:-	14:22924284:-	14:22922752:-	14:22922493:-	14:22922462:-	14:22922192:-	14:22921049:-	14:22920707:-	14:22920672:-
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP f6YSioLdAWpr Mk6ShCGm6RBJ XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	834aFpha8RvT dA7YoLwHrzgR JASnTTw2HeNE ksEP666umrV9 NKGM8wdLLrnu ZuM5xpZmNuDL	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3kRDPWwiRCgi L6w2k2VEv4EY	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	nfCHyrYzE6fB BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8