DNAmoreDB - A Database of Deoxyribozymes

DNAzyme description

 Reaction  Reacting groups  Substrates  Metal ion  Seq description
Diels-Alder Group 1 - Anthracene

Group 2 - DTME (dithiobismaleimidoethane)

L: DTME
R: DNA-HEG-anthracene
Mn2+
Mg2+
Zn2+
Ca2+
Cu2+
Co2+
N *
 Buffer conditions
50 mM Tris pH 7.5, 200 mM NaCl, 100 mM KCl, 20 mM MgCl2, 20 mM CaCl2, 5 µM MnCl2, 5 µM CoCl2, 5 µM CuCl2, 5 µM ZnCl2,
 Catalytic region of the DNAzyme
CAGAGGCTGTGACGGGACTTGGGGGTGGGAGTCGTT
Notes
Partially randomized catalytic region based on the 39M49 ribozyme, synthesized as DNA.

 Reported in...

Year of Publication First Author Laboratory Title PubMed ID DOI Reaction
2008 M Chandra S K Silverman DNA and RNA can be equally efficient catalysts for carbon-carbon bond formation. 18271591 10.1021/ja7111965 Diels-Alder

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