DNAmoreDB - A Database of Deoxyribozymes

DNAzyme description

 Reaction  Reacting groups  Substrates Product  Metal ion Linkage  Seq description
RNA ligation Group 1 - internal 2'-OH

Group 2 - 5'-triphosphate

L: GGAAGUCUCAUGUACUAACA
R: GUAUGUUCUAGCGCGGA
branched RNA Mn2+
A18 N 40
 Buffer conditions
50 mM HEPES pH 7.5, 150 mM NaCl, 2 mM KCl, 20 mM MnCl2
 Catalytic region of the DNAzyme
CGCACGGTCTGGTGTGGAAGCCAGGTTGCCTCCCTGCAAA

 Reported in...

Year of Publication First Author Laboratory Title PubMed ID DOI Reaction
2005 Y Wang S K Silverman Directing the outcome of deoxyribozyme selections to favor native 3'-5' RNA ligation. 15723545 10.1021/bi0478291 RNA ligation

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