DNAmoreDB - A Database of Deoxyribozymes

DNAzyme description

 Reaction  Reacting groups  Substrates Product  Metal ion Linkage  Seq description
RNA cleavage Group 1 - 2'-OH

Group 2 - vicinal phosphate

X: m6A
S: AUAGACUGAAUGAAGGXCUUCCGUAACU
n.d. Mg2+
RNA phosphodiester N 20
 Buffer conditions
50 mM Tris-HCl pH 7.5, 150 mM NaCl, 5 mM MgCl2
 Catalytic region of the DNAzyme
GATTCCAGGGCTTGAGGAGG

 Reported in...

Year of Publication First Author Laboratory Title PubMed ID DOI Reaction
2018 M V Sednev C Höbartner N -Methyladenosine-Sensitive RNA-Cleaving Deoxyribozymes. 30276938 10.1002/anie.201808745 RNA cleavage

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